Protein Interaction Antibody Pairs
American Research Products Inc PrEST Antigen CDKN2B
PrEST Antigen CDKN2B antigen APrEST88029 for cyclin-dependent kinase inhibitor 2B (p15 inhibits CDK4) Recombinant protein fragment of Human CDKN2B
American Research Products Inc PrEST Antigen PRKCB
PrEST Antigen PRKCB antigen APrEST87502 for protein kinase C beta Recombinant protein fragment of Human PRKCB
ABclonal Technology Phospho-HDAC2-S394 Rabbit pAb
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
American Research Products Inc PrEST Antigen CDC6
PrEST Antigen CDC6 antigen APrEST85305 for cell division cycle 6 Recombinant protein fragment of Human CDC6
ABclonal Technology MAP3K11 Rabbit pAb
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Sino Biological Recombinant Human RELA/NF-kappa B p65 Protein, Biotinylated 20
A DNA sequence encoding the Human RELA/NF-kappa B p65 (Q04206-1) (Met1-Tyr306) was expressed. The purified protein was biotinylated in vitro.
ABclonal Technology PLC gamma 1 (PLCG1) Rabbit mAb
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Sino Biological Recombinant Human Calreticulin/CALR Protein (Low Endotoxin)
A DNA sequence encoding the Human CALR (P27797) (Met1-Ala413) was expressed.
ABclonal Technology NTF4 Rabbit pAb
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
ABclonal Technology MYL2 Rabbit mAb
This gene encodes a major sarcomeric protein in mammalian striated muscle. The encoded protein plays a role in embryonic heart muscle structure and function, while phosphorylation of the encoded protein is involved in cardiac myosin cycling kinetics, torsion and function in adults. Mutations in this gene are associated with hypertrophic cardiomyopathy 10 and infant-onset myopathy.
ABclonal Technology MYL2 Rabbit mAb
This gene encodes a major sarcomeric protein in mammalian striated muscle. The encoded protein plays a role in embryonic heart muscle structure and function, while phosphorylation of the encoded protein is involved in cardiac myosin cycling kinetics, torsion and function in adults. Mutations in this gene are associated with hypertrophic cardiomyopathy 10 and infant-onset myopathy.
ABclonal Technology Fyn Rabbit mAb
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.