Donkey Secondary Antibodies
Biotium Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (KRTL/1377), CF647 conjugate, 0.1mg/mL
This MAb recognizes the 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium MAML3 (Mastermind Like Transcriptional Coactivator 3) (MAML3/1303), CF647 conjugate, 0.1mg/mL
MAML3 (mastermind-like protein 3) is a nuclear speckle protein that acts as a transcriptional coactivator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAML3 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, MAML3 interacts with the ankyrin repeats of the Notch proteins Notch 1, Notch 2, Notch 3 and Notch 4.This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-J, a complex that can then induce HES1 gene expression. While the N-terminal domain of MAML3 is essential for proper Notch binding, the C-terminal domain of MAML3 is essential for transcriptional activation. Due to its involvement in cell signaling and transcriptional activation, upregulation of MAML3 is thought to be involved in oncogenesis.Primary antibodies
Biotium CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), CF647 conjugate, 0.1mg/mL
This antibody recognizes a protein of 30-33 kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin's disease, par
Jackson Immuno Research Labs Alkaline Phosphatase-AffiniPure F(ab')2 Fragment Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
Alkaline Phosphatase-AffiniPure F(ab')2 Fragment Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
Jackson Immuno Research Labs 6 nm Colloidal Gold-AffiniPure Donkey Anti-Sheep IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot) (EM Grade)
6 nm Colloidal Gold-AffiniPure Donkey Anti-Sheep IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot) (EM Grade)
Jackson Immuno Research Labs Cy3-AffiniPure Donkey Anti-Mouse IgM µ Chain Specific
Cy3-AffiniPure Donkey Anti-Mouse IgM µ Chain Specific
Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure Donkey Anti-Sheep IgG (H+L)
Rhodamine Red-X-AffiniPure Donkey Anti-Sheep IgG (H+L)
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure F(ab')2 Fragment Donkey Anti-Human IgM Fc5µ Fragment Specific (min X Bov Hrs Sr Prot)
Alexa Fluor 594-AffiniPure F(ab')2 Fragment Donkey Anti-Human IgM Fc5µ Fragment Specific (min X Bov Hrs Sr Prot)
Biotium Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), CF488A conjugate, 0.1mg/mL
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins pres
Biotium Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (KRTL/1577R), CF488A conjugate, 0.1mg/mL
This MAb recognizes the 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Jackson Immuno Research Labs Alkaline Phosphatase-AffiniPure Donkey Anti-Human IgM Fc5µ Fragment Specific (min X Bov Hrs Sr Prot)
Alkaline Phosphatase-AffiniPure Donkey Anti-Human IgM Fc5µ Fragment Specific (min X Bov Hrs Sr Prot)