Mouse Secondary Antibodies
Biotium Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) (IGHM/2559R), CF594 conjugate, 0.1mg/mL
This antibody recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.Primary antibodies are available purifi
Biotium Human Herpes Virus 8 (HHV8)(HHV8/3606), CF740 conjugate, 0.1mg/mL
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biolegend Purified anti-mouse IL-15
Purified anti-mouse IL-15 [W19387G]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: Direct ELISA; Size: 100 μg
Cayman Chemical SchIsndrIn A 50mg
A lignan with diverse biological activities; binds to adiponectin receptor 2 (IC50 = 3.2 µM); reduces LPS-induced production of NO, IL-6, and TNF-α and apoptosis in primary mouse microglial cells at 10, 20, and 50 µM; reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells at 20 µM; reverses Aβ42-induced short-term and spatial memory deficits, as well as decreases in cerebral SOD and GPX activities in a mouse model of Alzheimer's disease at 4, 12, and 36 mg/kg
Biotium Human Lambda Light Chain(LcN-2), CF740 conjugate, 0.1mg/mL
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-CDK1 (Thr15) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-CDK1 (Thr15) Detection Kit, 50,000 Assay Points
Medchemexpress LLC Mouse Anti-Human IgG Fc | 5 MG
Mouse Anti-Human IgG Fc is a mouse-derived, non-conjugated IgG2a recombinant monoclonal antibody specifically targeting IgG Fc. It is expressed from CHO cells, with a heavy chain type of mIgG2a and a light chain type of mkappa. This product is intended for research use only.
- Mouse-derived, non-conjugated IgG2a recombinant monoclonal antibody
- Targets IgG Fc
- Expressed from CHO cells
- Predicted band size: 147.4 kDa
- Affinity purified
- Supplied in 0.01M phosphate buffered saline, pH 7.2, containing 1% BSA, 50% glycerol, and 0.05% sodium azide
- Stored at -20°C for 1 year, protected from light
- Avoid repeated freeze/thaw cycles
Biotium CD59 (heavy chain of Protectin)(BRA-10G), CF568 conjugate, 0.1mg/mL
Reacts with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement-mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions.Primary antibodies are available purified,
Cayman Chemical a-LInolenoyl EthnolamIde 10mg
An endocannabinoid containing α-linolenic acid in place of the arachidonate moiety of AEA; detected in porcine brain, but its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated
Medchemexpress LLC IgG4 Fc Human HEK2 10ug
Recombinant human IgG4 Fc domain (E99-G326), expressed in HEK293 cells and supplied as a tag-free, lyophilized protein with mammalian glycosylation. Intended for antibody engineering, Fc functional assays, and assay development.
Biotang Inc MUS ANTI HUM; Heat Shock Protein 90kDa Beta (GRP94) Member 1
MUS ANTI HUM; Heat Shock Protein 90kDa Beta (GRP94) Member 1
Biotang Inc MUS ANTI HUM; Glycogen synthase kinase-3 beta
MUS ANTI HUM; Glycogen synthase kinase-3 beta