Rabbit Secondary Antibodies
ABclonal Technology TCEB2 Rabbit mAb
This gene encodes the protein elongin B which is a subunit of the transcription factor B (SIII) complex The SIII complex is composed of elongins A A2 B and C It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units Elongin A functions as the transcriptionally active component of the SIII complex whereas elongins B and C are regulatory subunits Elongin A2 is specifically expressed in the testis and capable of forming a stable complex with elongins B and C The von Hippel-Lindau tumor suppressor protein binds to elongins B and C and thereby inhibits transcription elongation Two alternatively spliced transcript variants encoding different isoforms have been described for this gene Pseudogenes have been identified on chromosomes 11 and 13
ABclonal Technology 450 Rabbit anti- FcYRI/CD64
Enables IgG binding activity and IgG receptor activity Acts upstream of or within several processes including antibody-dependent cellular cytotoxicity endocytosis and positive regulation of hypersensitivity Located in external side of plasma membrane Is expressed in liver Orthologous to several human genes including FCGR1A (Fc gamma receptor Ia)
ABclonal Technology MLH3 Rabbit mAb
This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination The protein encoded by this gene functions as a heterodimer with other family members Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7) Several alternatively spliced transcript variants have been identified but the full-length nature of only two transcript variants has been determined
Genscript Corporation MonoRab Rabbit Anti-scFv Cock
This product is specific for scFvs in various species (humanized mouse) various orders (VH-linker-VL VL-linker-VH) and various forms of scFv-based bispecific antibodies(DART BiTE TandAbs IgG(H)-scFv2 scFv-Fab-Fc etc) This product exhibits minimal cross-reactivity with human mouse goat and rabbit immunoglobulins
ABclonal Technology B-Actin Rabbit mAb
This gene encodes one of six different actin proteins Actins are highly conserved proteins that are involved in cell motility structure integrity and intercellular signaling The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed Mutations in this gene cause Baraitser-Winter syndrome 1 which is characterized by intellectual disability with a distinctive facial appearance in human patients Numerous pseudogenes of this gene have been identified throughout the human genome
ABclonal Technology Rab12 Rabbit mAb MJFF-A-3F6
Rab12 a member of the RAS oncogene family is crucial for intracellular membrane trafficking This small GTPase transports vesicles from recycling endosomes to lysosomes and is essential for autophagy and transferrin receptor degradation Rab12 cycles between inactive GDP-bound and active GTP-bound forms recruiting effectors for vesicle movement and fusion It is phosphorylated by LRRK2 (Leucine-Rich Repeat Kinase 2) and also regulates LRRK2 activity Rab12 activates LRRK2 which increases phosphorylation of Rab10 another trafficking protein especially in lysosomal damage Dysregulation of this pathway due to LRRK2 mutations is linked to neurodegeneration in Parkinson s disease
ABclonal Technology GMNN Rabbit mAb
This gene encodes a protein that plays a critical role in cell cycle regulation The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1 preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition Increased expression of this gene may play a role in several malignancies including colon rectal and breast cancer Alternatively spliced transcript variants have been observed for this gene and two pseudogenes of this gene are located on the short arm of chromosome 16
ABclonal Technology PE Rabbit anti-Mouse CD40 mAb
Predicted to enable antigen binding activity protein domain specific binding activity and ubiquitin protein ligase binding activity Involved in B cell mediated immunity CD40 signaling pathway and cellular calcium ion homeostasis Acts upstream of or within several processes including defense response to other organism positive regulation of B cell activation and positive regulation of interleukin-12 production Located in external side of plasma membrane and intracellular membrane-bounded organelle Part of CD40 receptor complex Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Human ortholog(s) of this gene implicated in several diseases including Kawasaki disease autoimmune disease (multiple) end stage renal disease hyperimmunoglobulin syndrome (multiple) and non-Hodgkin lymphoma (multiple) Orthologous to human CD40 (CD40 molecule)
ABclonal Technology Nup107 Rabbit mAb
This gene encodes a member of the nucleoporin family The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC) All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized
ABclonal Technology Claudin18.2 Rabbit mAb
This gene encodes a member of the claudin family Claudins are integral membrane proteins and components of tight junction strands Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas PKC MAPK AP-1 (protein kinase C mitogen-activated protein kinase activator protein-1) dependent pathway regulates the expression of this gene in gastric cells Alternatively spliced transcript variants encoding different isoforms have been identified
![Abcam Rabbit monoclonal [M87-3] Anti-Mouse IgG1, IgG2a, IgG2b H&L](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2219534.png-250.jpg)
Abcam Rabbit monoclonal [M87-3] Anti-Mouse IgG1, IgG2a, IgG2b H&L
Rabbit monoclonal [M87-3] Anti-Mouse IgG1, IgG2a, IgG2b H&L
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical IgDhumn RabbIt Monclonal 100ug
Immunogen: Human IgD • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) IgD; (-) Human IgG, IgM, IgA, IgE • Applications: ELISA
Jackson Immuno Research Labs AffiniPure Rabbit Anti-Human IgG + IgM (H+L) (min X Ms Sr Prot)
AffiniPure Rabbit Anti-Human IgG + IgM (H+L) (min X Ms Sr Prot)
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure Rabbit Anti-Human Serum IgA α Chain Specific
Fluorescein (FITC)-AffiniPure Rabbit Anti-Human Serum IgA α Chain Specific
Abcam Rabbit Anti-Human IgM mu chain (HRP)
Rabbit Anti-Human IgM mu chain (HRP)
The product is subject to the following: Abcam Restricted Use Statement