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Filtered Search Results
Electron Microscopy Sciences Aurion ImmunoGold Rabbit-anti-Sheep IgG (H&L), UltraSmall 1.5 ML
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Ultra small conjugates have far less influence on the adsorbed antibodies or detecting molecules, thus behave as though they are uncoupled. Used with R-Gent SE-LM and SE-EM silver enhancement reagents they are the best choice for any application.
Particle size: UltraSmall
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Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure Rabbit Anti-Human IgG F(ab')2 Fragment Specific
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Alexa Fluor 488-AffiniPure Rabbit Anti-Human IgG F(ab')2 Fragment Specific
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ABclonal Technology 594 Rabbit anti-Human Nectin-4
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Nectin-4 poliovirus Receptor-like 4 (PVRL4) is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily that promotes intercellular adhesion by acting as a major component of adhesion junctions The extracellular domain of Nectin-4 consists of one Ig variable region (V) and two Ig constant regions (C) which mediate binding to measles virus and adjacent cells through trans-heterophile interactions with Nectin-1 Unlike other members of the connectin family which are widely expressed in adult tissues human Nectin-4 expression is largely limited to the blastoderm Studies have shown that Nectin-4 is overexpressed in cells from a variety of human solid tumors including pancreatic breast lung and ovarian cancers The expression pattern of Nectin-4 in normal tissues is limited so NECTIN-4 can be used as a novel therapeutic target for various human tumors
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Jackson Immuno Research Labs Rhodamine (TRITC)-AffiniPure Rabbit Anti-Human Lactoferrin
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Rhodamine (TRITC)-AffiniPure Rabbit Anti-Human Lactoferrin
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Jackson Immuno Research Labs Biotin-SP-AffiniPure Rabbit Anti-Human IgG + IgM (H+L) (min X Ms Sr Prot)
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Biotin-SP-AffiniPure Rabbit Anti-Human IgG + IgM (H+L) (min X Ms Sr Prot)
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Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure F(ab')2 Fragment Rabbit Anti-Human IgG (H+L)
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Rhodamine Red-X-AffiniPure F(ab')2 Fragment Rabbit Anti-Human IgG (H+L)
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ABclonal Technology 647 Rabbit anti-Human CD8b
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system The CD8 antigen acting as a coreceptor and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules The functional coreceptor is either a homodimer composed of two alpha chains or a heterodimer composed of one alpha and one beta chain Both alpha and beta chains share significant homology to immunoglobulin variable light chains This gene encodes the CD8 beta chain isoforms Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described A pseudogene also located on chromosome 2 has been identified
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ABclonal Technology 610 Rabbit anti-Human CD45
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitosis and oncogenic transformation This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus is classified as a receptor type PTP This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling Alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported
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ABclonal Technology 594 Rabbit anti-Human CD46
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The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I which protects the host cell from damage by complement In addition the encoded protein can act as a receptor for the Edmonston strain of measles virus human herpesvirus-6 and type IV pili of pathogenic Neisseria Finally the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome Alternatively spliced transcript variants encoding different isoforms have been described
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ABclonal Technology 594 Rabbit anti-Human Nectin-4
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Nectin-4 poliovirus Receptor-like 4 (PVRL4) is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily that promotes intercellular adhesion by acting as a major component of adhesion junctions The extracellular domain of Nectin-4 consists of one Ig variable region (V) and two Ig constant regions (C) which mediate binding to measles virus and adjacent cells through trans-heterophile interactions with Nectin-1 Unlike other members of the connectin family which are widely expressed in adult tissues human Nectin-4 expression is largely limited to the blastoderm Studies have shown that Nectin-4 is overexpressed in cells from a variety of human solid tumors including pancreatic breast lung and ovarian cancers The expression pattern of Nectin-4 in normal tissues is limited so NECTIN-4 can be used as a novel therapeutic target for various human tumors
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Abcam Rabbit Anti-Human IgG H&L (FITC) preadsorbed.
Rabbit Anti-Human IgG H&L (FITC) preadsorbed.
The product is subject to the following: Abcam Restricted Use Statement
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ABclonal Technology PE Rabbit anti-Human IgA1 mAb
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Ig alpha is the major immunoglobulin class in body secretions It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system In normal adult serum the approximate percentage composition of IgA with respect to is subclasses is IgA1 90% and IgA2 10% In secretory IgA the subclass proportions may approach 50 50 The clinical significance of the subclasses has yet to be determined
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ABclonal Technology PE Rabbit anti-Human TMPRSS2
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This gene encodes a protein that belongs to the serine protease family The encoded protein contains a type II transmembrane domain a receptor class A domain a scavenger receptor cysteine-rich domain and a protease domain Serine proteases are known to be involved in many physiological and pathological processes This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E MERS-CoV SARS-CoV and SARS-CoV-2 (COVID-19 virus) Alternatively spliced transcript variants encoding different isoforms have been found for this gene
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ABclonal Technology 594 Rabbit anti-Human ROR1
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This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia Alternative splicing results in multiple transcript variants encoding different isoforms
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Abcam Rabbit Anti-Human IgA alpha chain
Rabbit Anti-Human IgA alpha chain
The product is subject to the following: Abcam Restricted Use Statement
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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