Rabbit Secondary Antibodies
ABclonal Technology Biotin Rabbit anti-Mouse CD19
Involved in several processes including B-1 B cell differentiation positive regulation of phosphatidylinositol 3-kinase activity and positive regulation of release of sequestered calcium ion into cytosol Acts upstream of or within B cell receptor signaling pathway Located in external side of plasma membrane Is integral component of plasma membrane Is expressed in liver and spleen Human ortholog(s) of this gene implicated in common variable immunodeficiency Orthologous to human CD19 (CD19 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD22 mAb
Enables CD4 receptor binding activity protein phosphatase binding activity and sialic acid binding activity Involved in several processes including negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production and regulation of B cell proliferation Located in external side of plasma membrane and neuronal cell body membrane Is integral component of plasma membrane Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Orthologous to human CD22 (CD22 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD88/C5aR
Enables complement component C5a receptor activity Involved in several processes including astrocyte activation positive regulation of vascular endothelial growth factor production and regulation of granulocyte chemotaxis Acts upstream of or within defense response to Gram-positive bacterium neutrophil chemotaxis and response to peptidoglycan Predicted to be located in several cellular components including apical part of cell basolateral plasma membrane and cell surface Predicted to be active in plasma membrane Is expressed in several structures including brain liver neural ectoderm and sensory organ Orthologous to several human genes including OPRPN (opiorphin prepropeptide)
Jackson Immuno Research Labs Alexa Fluor 647-AffiniPure Rabbit Anti-Mouse IgM µ Chain Specific (min X Hu Sr Prot)
Alexa Fluor 647-AffiniPure Rabbit Anti-Mouse IgM µ Chain Specific (min X Hu Sr Prot)
ABclonal Technology PE Rabbit anti-Mouse CD94 mAb
CD94 is a 43 39 kD C-type lectin also known as Kp43 It is present on all NK cells NKT cells and a subset of CD8-positive T lymphocytes in most mouse strains CD94 is a type-II transmembrane protein with an extracellular lectin-like domain and a short cytoplasmic tail CD94 is expressed as a disulphide-linked heterodimer with a NKG2 subunit believed to mediate signal transduction When associated with NKG2A the complex triggers inhibition when associated with NKG2C the complex triggers stimulation The receptor complex of CD94 and NKG2 receptors bind to the ligand Qa-1 and are thought to play a role in maintaining self-tolerance in developing NK cells
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure Rabbit Anti-Human IgG F(ab')2 Fragment Specific
Alexa Fluor 594-AffiniPure Rabbit Anti-Human IgG F(ab')2 Fragment Specific
ABclonal Technology 647 Rabbit anti-Human Syk
This gene encodes a member of the family of non-receptor type Tyr protein kinases This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses including proliferation differentiation and phagocytosis It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 450 Rabbit anti-Human EGFR
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily This protein is a receptor for members of the epidermal growth factor family EGFR is a cell surface protein that binds to epidermal growth factor thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation Mutations in this gene are associated with lung cancer EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
ABclonal Technology 488 Rabbit anti-Human CD42b
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer an alpha chain and a beta chain that is linked by disulfide bonds The Gp Ib functions as a receptor for von Willebrand factor (VWF) The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury and also initiates signaling events within the platelet that lead to enhanced platelet activation thrombosis and hemostasis This gene encodes the alpha subunit Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy
Human IGHG1 PAb 100ul (Sino Biological)
Produced in rabbits immunized with recombinant human IgG1-Fc (Catalog#10702-HNAH; P01857-1; Glu99-Lys330,C103S). This polyclonal antibody was purified by antigen affinity chromatography.
ABclonal Technology 488 Rabbit anti-Human CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit This gene is expressed not only in T lymphocytes but also in B cells macrophages granulocytes as well as in various regions of the brain The protein functions to initiate or augment the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene
ABclonal Technology PE Rabbit anti-Human TLR1 mAb
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity TLRs are highly conserved from Drosophila to humans and share structural and functional similarities They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity The various TLRs exhibit different patterns of expression This gene is ubiquitously expressed and at higher levels than other TLR genes Different length transcripts presumably resulting from use of alternative polyadenylation site and or from alternative splicing have been noted for this gene
ABclonal Technology 488 Rabbit anti-Human CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily This protein is expressed by antigen-presenting cells and it is the ligand for two proteins at the cell surface of T cells CD28 antigen and cytotoxic T-lymphocyte-associated protein 4 Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response Alternative splicing results in several transcript variants encoding different isoforms
ABclonal Technology 488 Rabbit anti-Human CD27
The protein encoded by this gene is a member of the TNF-receptor superfamily This receptor is required for generation and long-term maintenance of T cell immunity It binds to ligand CD70 and plays a key role in regulating B-cell activation and immunoglobulin synthesis This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8 JNK Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor CD27-binding protein (SIVA) a proapoptotic protein can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
Medchemexpress LLC IgG2B Fc Llama HEK 5ug | 5ug
IgG2B Fc Protein Llama (HEK293) is the recombinant IgG2B Fc protein expressed by HEK293 with tag free