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Filtered Search Results
ABclonal Technology 647 Rabbit anti-Human CD66b
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Enables protein heterodimerization activity Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Located in cell surface and extracellular space Biomarker of severe acute respiratory syndrome
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ABclonal Technology 647 Rabbit anti-Human CD200R
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a receptor for the OX-2 membrane glycoprotein Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner Alternative splicing of this gene results in multiple transcript variants
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ABclonal Technology 647 Rabbit anti-Human CD200R
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a receptor for the OX-2 membrane glycoprotein Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner Alternative splicing of this gene results in multiple transcript variants
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ABclonal Technology 450 Rabbit anti-Human CD59
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis and it is involved in lymphocyte signal transduction This protein is a potent inhibitor of the complement membrane attack complex whereby it binds complement C8 and or C9 during the assembly of this complex thereby inhibiting the incorporation of multiple copies of C9 into the complex which is necessary for osmolytic pore formation This protein also plays a role in signal transduction pathways in the activation of T cells Mutations in this gene cause CD59 deficiency a disease resulting in hemolytic anemia and thrombosis and which causes cerebral infarction Multiple alternatively spliced transcript variants which encode the same protein have been identified for this gene
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ABclonal Technology 594 Rabbit anti-Human CD142
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes coagulation factor III a cell surface glycoprotein that initiates blood coagulation cascades by acting as a high-affinity receptor for factor VII The complex formed activates specific proteolysis initiating coagulation Unlike other cofactors factor III is fully functional when expressed on cell surfaces like monocytes It has extracellular transmembrane and cytoplasmic domains Platelets and monocytes express this factor under procoagulatory and proinflammatory conditions and it plays a role in HIV-associated coagulopathy Factor III expression in platelets and monocytes is linked to COVID-19 severity and mortality Congenital deficiency of this factor has not been observed Alternative splicing produces multiple transcript variants
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ABclonal Technology PE Rabbit anti-Human IL9 mAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells This cytokine stimulates cell proliferation and prevents apoptosis It functions through the interleukin 9 receptor (IL9R) which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes The gene encoding this cytokine has been identified as a candidate gene for asthma Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness
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ABclonal Technology 647 Rabbit anti-Human CD204
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes class A macrophage scavenger receptors which produce three isoforms (1 2 and 3) via alternative splicing These trimeric integral membrane glycoproteins are macrophage-specific and involved in various processes like atherosclerosis Alzheimer s disease and host defense Isoforms 1 and 2 mediate the endocytosis of modified low-density lipoproteins (LDLs) while isoform 3 despite having the necessary domain cannot internalize modified LDL due to altered intracellular processing and trapping within the endoplasmic reticulum Isoform 3 also inhibits the function of isoforms 1 and 2 when co-expressed suggesting a regulatory mechanism for scavenger receptor activity in macrophages
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ABclonal Technology 647 Rabbit anti-Human IL-5
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils The encoded cytokine plays a major role in the regulation of eosinophil formation maturation recruitment and survival The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases This cytokine functions by binding to its receptor which is a heterodimer whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2 GM-CSF) This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4) interleukin 13 (IL13) and CSF2 This gene IL4 and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31
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ABclonal Technology 488 Rabbit anti-Human CD1B
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a member of the CD1 family of transmembrane glycoproteins which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification to bind lipid antigens
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ABclonal Technology 488 Rabbit anti-Human CD24
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface This gene was missing from previous genome assemblies but is properly located on chromosome 6 Non-transcribed pseudogenes have been designated on chromosomes 1 15 20 and Y Alternative splicing results in multiple transcript variants
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ABclonal Technology 700 Rabbit anti-Human CD1c
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a member of the CD1 family of transmembrane glycoproteins which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail Alternatively spliced transcript variants of this gene have been observed but their full-length nature is not known
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ABclonal Technology 488 Rabbit anti-Human CD24
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface This gene was missing from previous genome assemblies but is properly located on chromosome 6 Non-transcribed pseudogenes have been designated on chromosomes 1 15 20 and Y Alternative splicing results in multiple transcript variants
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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ABclonal Technology 594 Rabbit anti-Human Syk
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a member of the family of non-receptor type Tyr protein kinases This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses including proliferation differentiation and phagocytosis It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas Alternatively spliced transcript variants encoding different isoforms have been found for this gene
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Immunoreagents Inc RABBIT A-LLAMA IGG FITC
Secondary Antibody; Rabbit anti-llama IgG (H&L) - Affinity Pure, FITC Conjugate, Host: Rabbit, Format: Liq, Label: FITC, Applications: WB, ELISA, IHC/ICC, IF, IP, FC, FACS
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Immunoreagents Inc RABBIT A-LLAMA IGG DYLIGHT550
Secondary Antibody; Rabbit anti-llama IgG (H&L) - Affinity Pure, DyLight 550 Conjugate, Host: Rabbit, Format: Lyo, Label: DyL550, Applications: WB, ELISA, IHC/ICC, IF, IP, FC, FACS
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