This 2'-O-methyl Uridine RNA CPG support is designed for synthesizing oligonucleotides with enhanced nuclease resistance. It functions similarly to standard nucleoside supports due to its 5'-Dimethoxytrityl (DMT) group, allowing for simplified deprotection, isolation, and handling comparable to those for oligodeoxynucleotides.
- Nucleoside: Uridine, 2'-O-methyl
- Support type: Controlled Pore Glass (CPG)
- Linker: 3'-succinoyl-long chain alkylamino
- Protecting group: 5'-Dimethoxytrityl (DMT)
- Application: Oligonucleotide synthesis
- Feature: Nuclease resistant linkages
- Synthesis scale: 1 μmole (per column)
- Pack size: 4 columns