PPACK Dihydrochloride is a small-molecule inhibitor targeting human -thrombin It is designed to inhibit thrombin activity thereby blocking downstream platelet aggregation and coagulation pathways PPACK Dihydrochloride exerts its biological activity primarily through selective irreversible inhibition of thrombin by covalently occupying the thrombin active-site serine residue and forming a stable tetrahedral intermediate with the catalytic His57 residue Based on these pharmacological properties PPACK Dihydrochloride holds research potential in biomedical studies as an anticoagulant reagent and for investigating thrombin-mediated coagulation and platelet activation mechanisms