Apoptosis Reagents and Kits
Selleck Chemical LLC Ganetespib (STA-9090) 5mg 888216-25-9
Ganetespib (STA-9090) is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells, induces apoptosis of OSA cells while normal osteoblasts are not affected; active metabolite of STA-1474. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Abcam Annexin V-iFluor 555 Apoptosis Staining / Detection Reagent.
Annexin V-iFluor 555 Apoptosis Staining / Detection Reagent.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc ANNEXIN V APC CYANINE7 PI APOP
5000265049 ANNEXIN V APC CYANINE7 PI APOP
Sigma Aldrich Fine Chemicals Biosciences In Situ Cell Death Detection Kit, TMR red, 56-81-5
In Situ Cell Death Detection Kit, TMR red
Biotium JC-1 Mitochondrial Membrane Potential Detection Kit (100 assays)
The loss of mitochondrial membrane potential is a hallmark for apoptosis. It is an early event preceding phosphatidylserine externalization and coinciding with caspase activation. JC-1 Mitochondrial Membrane Potential Detection Kit is used to measure mitochondrial membrane potential changes in cells. In non-apoptotic cells, JC-1 accumulates as aggregates in the mitochondrial membranes, resulting in red fluorescence (590 nm). The brightness of red fluorescence is proportional to the potential and varies among different cell types. However, in apoptotic and necrotic cells, which have diminished mitochondrial membrane potential, JC-1 exists in the green fluorescent (529 nm) monomeric form. This kit provides a step-by-step protocol and ready-to-use reagents for performing assays for flow cytometry, fluorescence microscopy, or fluorometric microplate reader.
Enzo Life Sciences Ac-DEVD-AFC (5 mg) CAS: 201608-14-2
Caspase-3 substrate. Fluorogenic substrate for caspase-3 (CPP32), with a Km=9.7µM) and related cysteine proteases. Sequence is based on PARP cleavage at Asp216 for caspase-3. Similar to Ac-DEVD-AMC (Prod. No. ALX-260-031) but the AFC fluorophore has a greater Stokes’ shift upon cleavage than AMC. Reaction can be monitored quantitatively or visually using a hand-held long-UV lamp and visualizing a blue to green shift in fluorescence upon cleavage. Ex.: 400nm, Em.: 505nm. Alternative Name: Caspase-3 substrate (fluorogenic). Formula: C30H34F3N5O13. MW: 729.6. CAS: 201608-14-2. Purity: ≥96% (HPLC). Sequence Ac-Asp-Glu-Val-Asp-AFC (AFC = 7-Amino-4-trifluoromethylcoumarin). Appearance: White to off-white powder. Solubility: Soluble in dimethyl formamide, DMSO or methanol; slightly soluble in water (0.4mg/ml). Long Term Storage: -20°C. Handling: Protect from light. Keep cool and dry.
Abcam Human Protein S Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Protein S Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Protein S.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human/Monkey IL-4 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human/Monkey IL-4 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human/Monkey IL-4.
The product is subject to the following: Abcam Restricted Use Statement