Apoptosis Reagents and Kits
Biolegend TotalSeqTM-B0863 anti-human CD
TotalSeq™-B0863 anti-human CD257 (BAFF, BLYS) [1D6]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: PG; Size: 10 μg
Apexbio Technology LLC Apoptosis Inhibitor 54135-60-3 10mg
Apoptosis Inhibitor (CAS 54135-60-3) is a small molecule that modulates apoptotic processes by antagonizing pathways involved in caspase-3-mediated cell death It has been shown to suppress Fas ligand-induced cytotoxicity in human WC8 cells (IC50 67 g/ml) and etoposide-induced apoptosis in U937 cells (IC50 130 g/ml) as well as reduce caspase-3 activation in U937 cells (IC50 79 g/ml) The compound does not directly inhibit caspase-3 enzymatic activity in vitro indicating an upstream mechanism In vivo administration leads to decreased numbers of apoptotic neurons and reduced caspase-3 cells in neural and regenerative models Apoptosis Inhibitor is a valuable tool for studying caspase-dependent apoptosis and tissue regeneration
Biolegend ApotrackerTM Tetra Alexa Fluor
Apotracker™ Tetra Alexa Fluor 647; Reactivity: Human, Mouse; Apps: FC; Size: 20 tests
Abcam Human CCND1 (Cyclin D1) knockout HeLa cell lysate.
Human CCND1 (Cyclin D1) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TUBB3 (beta III Tubulin) knockout HeLa cell lysate.
Human TUBB3 (beta III Tubulin) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human MUC1 knockout HeLa cell lysate.
Human MUC1 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human SPR knockout HeLa cell lysate.
Human SPR knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC GSK2656157 50mg 1337532-29-2
GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM in a cell-free assay, 500-fold greater against a panel of 300 kinases. GSK2656157 decreases apoptosis and inhibits excessive autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Z-VAD(OMe)-FMK (5mg). CAS: 187389-52-2
Irreversible and cell permeable broad-spectrum caspase inhibitor. Inhibits Fas-mediated apoptosis in Jurkat T cells and apoptosis in THP.1 cells induced by diverse stimuli (including cycloheximide, thapsigargin, etoposide and staurosporine). For cell free assays use ALX-260-020. Alternative name: Caspase family inhibitor (fluoromethylketone). Purity: ≥95%. Solubility: Soluble in DMSO (>10mg/ml), dimethyl formamide (7mg/ml) or 100% ethanol (1.3mg/ml). Long Term Storage: -20°C.
Selleck Chemical LLC LCL161 5mg 1005342-46-0
LCL-161, a small molecule second mitochondrial activator of caspase (SMAC) mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC RG-7112 5mg 939981-39-2 RO5045337
RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor with HTRF IC50 of 18 nM. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Apoptosis Activator 2 (25mg). CAS: 79183-19-0
Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome, triggering caspase-9 activation resulting in activated caspase-3. Shows strong selectivity for cancer cells against normal cell lines. Acts in a similar way like apoptosis inducer PETCM (ALX-420-031). Alternative name: 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (5mg/ml), methanol (5mg/ml) or 100% ethanol. Long Term Storage: +4°C.
Enzo Life Sciences Genipin (100mg). CAS: 6902-77-8
Cell permeable inhibitor of uncoupling protein 2 (UCP2). Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Induces apoptosis. Protein cross-linking agent. Anti-inflammatory and anti-angiogenic. Alternative name: (+)-Genipin, Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate. Purity: ≥98% (HPLC). Appearance: White to off-white crystalline solid. Solubility: Soluble in DMSO (50mg/ml), dimethyl formamide (25mg/ml), 100% ethanol (5mg/ml), methanol or ethyl acetate; insoluble in water. Long Term Storage: -20°C.
Abcam Human MLH1 knockout HeLa cell lysate.
Human MLH1 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human FABP5 knockout HeLa cell lysate.
Human FABP5 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement