Apoptosis Reagents and Kits
Abcam Human NCR1 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human NCR1 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human NCR1.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Angiopoietin-like 4/ANGPTL4 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Angiopoietin-like 4/ANGPTL4 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Angiopoietin-like 4/ANGPTL4.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Granzyme B Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Granzyme B Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Granzyme B.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Ac-AAVAlPAVlAlAP-VAD-CHO 1mg
A composite of a non-selective caspase inhibitor and a cell-permeable hydrophobic sequence; a non-selective caspase inhibitor
Biotium Dual Apoptosis Assay with NucView 488 Caspase-3 Substrate and CF594 Annexin V (50 assays)
This kit includes two apoptosis markers, NucView 488 Caspase-3 Substrate (green) and CF594 conjugated Annexin (red), for profiling apoptotic cells with respect to two important apoptosis events, caspase-3 activation and phosphatidylserine (PS) translocation, by flow cytometry or fluorescence microscopy.Unlike traditional fluorogenic caspase substrates that inhibit caspase activity or require cell lysis, NucView 488 a novel fluorogenic caspase-3 substrate, is non-inhibitory to caspases, and permits apoptosis detection within individual intact cells, in real-time. The non-fluorescent substrate is cleaved by caspase-3/7 in apoptotic cells releasing a high-affinity DNA dye that migrates to the nucleus and emits bright green fluorescence, allowing caspase-3/7 detection and visualization of apoptotic nuclear morphology. Exposed PS on apoptotic cells is detected by Annexin V conjugated to CF594 (Abs/Em: 593/614 nm), a bright and photostable deep red dye spectrally similar to Texas Red.
Meso Scale Discovery R-PLEX Human Caspase-1 ASYQP
The R-Plex Human Caspase-1 Assay Kit from Meso Scale Discovery is used to quantitatively measure caspase-1 in human biological samples such as serum plasma cell culture supernatants and cell lysates The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity a broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag and calibrator diluent The assay takes approximately 3 5 hours to complete after a 2 hour incubation period The kit can perform up to 94 assays in the 96-well plate format
Apexbio Technology LLC Caspase-3 Colorimetric Assay Kit,25 assays
Cysteine-dependent aspartate-directed proteases (Caspases) are a family of cysteine proteases that play important roles in apoptosis, necrosis, and inflammation. Sequential activation of caspases plays an important role in cell apoptosis. Caspase-3 is a caspase protein that cleaves and activates caspases 6 and 7, and is processed and activated by caspases 8, 9, and 10. Caspase-3 is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with Alzheimer's disease. Caspase-3 recognizes tetra-peptide sequences D-x-x-D and hydrolyzes peptide bonds after aspartic acid residues.Caspase-3 Colorimetric Assay Kit provides a convenient and simple way for detecting the DEVD-dependent caspase activity. Other sizes are also available. Please inqury us for quote.
Abcam Human TK1 (Thymidine Kinase 1) knockout HEK-293T cell lysate.
Human TK1 (Thymidine Kinase 1) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences NUCLEAR-ID Green chromatin condensation detection kit (1Kit)
The NUCLEAR-ID Green Chromatin Condensation Detection Kit detects nuclear condensation using a DNA intercalating dye that brightly stains the condensed chromatin of apoptotic cells, but only dimly stains the uncondensed chromatin of healthy living cells. Mechanism of Action The cell-permeable dye used in this application is an aromatic, planar cationic structure that inserts between stacked base pairs on the DNA duplex, providing an environmentally-dependent fluorescence enhancement of the dye molecules and large increases in fluorescence signal relative to the free dye in solution. Since the signal enhancement provides a proportional response, direct quantitation of DNA is possible. Further signal increase is observed upon DNA condensation during apoptosis.Applications: Flow Cytometry, Fluorescence microscopy, Fluorescent detection .
Cayman Chemical Z-VAD-AMCacetate 1mg
A caspase-1 fluorogenic substrate; upon enzymatic cleavage, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 340-360/440-460 nm, respectively