Signal Transduction Reagents and Kits
Sigma Aldrich Fine Chemicals Biosciences Calpeptin >=98% (HPLC) | 117591-20-5 | MFCD00155623 | 5MG
Calpeptin >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 362.46 | 117591-20-5 | MFCD00155623 | 5MG
Echelon Biosciences Research Labs PI(5)P DIC8 AMMONIUM SALT 500 ug
Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Echelon Biosciences Research Labs SHUTTLE PIP KIT PI(5)P
Echelon Biosciences - Shuttle PIP Kit - P-9005 - PI(5)P This item is non returnable
Echelon Biosciences Research Labs LINOLENOYL LPA 10 mg
Linolenoyl LPA, 18:3 is an LPA analog with an unsaturated acyl chain. Lysophosphatidic Acid (LPA) is a small lysophospholipid involved in diverse cellular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogenesis, tumor invasion, and smooth muscle contraction. LPA binds to several G-coupled protein receptors to initiate its biological functions. In cancer, LPA primarily promotes cell survival, migration and invasion. May contain up to 5-10% of the 2-acyl isomer due to acyl transfer. This item is non returnable
Carnabio Usa Inc CK1G1(CSNK1G1)/5UG/FULL-LENGTH
CK11(CSNK1G1), Full-length, Wild type, Amino Acid 1-422, NP_071331.2, Expressed in Insect (sf21); 5microg
Enzo Life Sciences 8-Bromo-cGMP (50mg). CAS: 51116-01-9
A cell-permeable cGMP analog which is more resistant to phosphodiesterases than cGMP and which preferentially activates cGMP-dependent protein kinase. It inhibits thrombin stimulated arachidonic acid release in human platelets. Purity: ≥96% (HPLC). Solubility: Soluble in water (25mg/ml) or aqueous buffers. Sparingly soluble in methanol (4mM). Insoluble in DMSO, dimethyl formamide and 96% ethanol. Long Term Storage: -20°C.
Enzo Life Sciences Sulindac sulfide (25mg). CAS: 32004-67-4
Active metabolite of sulindac (ALX-430-105). Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling. Alternative name: Z-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid. Purity: ≥99% (TLC). Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (5mg/ml, warm). Long Term Storage: Ambient.
Echelon Biosciences Research Labs 1-Hydroxy-2-methyl-2-buten-4-yl 4-diphosphate (HDMAPP) 10 mg
1-Hydroxy-2-methyl-2-buten-4-yl 4-diphosphate (HDMAPP or HMBPP) is an intermediate in the non-mevalonate pathway and is biosynthesized from 2-C-Methyl-D-erythritol 2,4-cyclophosphate (cMEPP) by IspG (GcpE). It is the substrate for IspH (LytB) yielding IPP and DMAPP. In addition, HDMAPP is the most potent VgVd T-cell activator identified. This item is non returnable
Echelon Biosciences Research Labs PI(3,4)P2 PolyPIPosomes 0.1 mL
PolyPIPosomes are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents. PolyPIPosomes are provided as a 1mM total lipid solution containing 5% PIP. Each order of 250 L or 1 mL of PolyPIPosomes includes 100 L of Control PolyPIPosomes. This item is non returnable
Abcam Glucose-6-Phosphate Assay Kit (Colorimetric)
Glucose-6-Phosphate Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Takara Bio Lenti-X GoStix Plus, 10 Minute quantitative lentiviral titer tests
Lenti-X GoStix Plus; Quantify lentivirus titer in 10 minutes; 50 Tests
Echelon Biosciences Research Labs APP gamma secretase inhibitor - 5 mg, CAS#:
APP gamma secretase inhibitor - 5mg , N-[N-(3,5-difluorophenacetyl)-Ala-S-Phenylglycine Methylester Category/Application: Enzyme Substrates This item is non returnable
Montana Molecular Green Ratiometric Cilia-Targeted cADDis cAMP Sensor Kit D0211G, 10mL, CMV
Measure real-time cAMP signaling kinetics in the primary cilia with this live cell fluorescent assay. Add cADDis to your cells and measure robust signals the next day on a fluorescence imaging system. Decreasing green fluorescence indicates ciliary cAMP increase. Constitutively expressed cytosolic red fluorescence can be used for ratiometric measurements. This assay is genetically encoded and packaged in BacMam for efficient delivery to cilia in most cell types, including many primary and iPSC-derived cells.