Signal Transduction Reagents and Kits
Medchemexpress LLC UK122 TFA | 940290-58-4 | 99.85% | 405.33 | 1 ML
UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. It exhibits little to no inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM). This 4-oxazolidinone analogue acts as an anticancer agent by inhibiting cancer cell migration and invasion.
- Potent and selective urokinase-type plasminogen activator (uPA) inhibitor.
- IC50 of 0.2 μM for uPA.
- Minimal inhibition of tPA, plasmin, thrombin, and trypsin (IC50 > 100 μM).
- 4-oxazolidinone analogue.
- Acts as an anticancer agent.
- Inhibits cancer cell migration and invasion.
- For research use only.
Enzo Life Sciences STA-21, (1mg), CAS Number: 28882-53-3
STAT inhibitor. STA-21 is a novel Stat3-selective inhibitor. It inhibits Stat3 dimerization and DNA binding as well as Stat3-dependent luciferase reporter activity. Alternative Name: (S)-Ochromycinone, Deoxytetrangomycin. Formula: C19H14O4. MW: 306.3. CAS Number: 28882-53-3. Purity: ≥98% (HPLC). Appearance: White to yellow solid. Solubility: Soluble in DMSO (20mg/ml). Use/Stability: Store solutions at -20°C for up to 3 months. Long Term Storage: -20°C
Carnabio Usa Inc CK1G1(CSNK1G1)/10UG/FULL-LENGT
CK11(CSNK1G1), Full-length, Wild type, Amino Acid 1-422, NP_071331.2, Expressed in Insect (sf21); 10microg
Apexbio Technology LLC highly selective, potent and cell-permeable p38 MAPK inhibitor 152121-30-7. MFCD00941964
highly selective, potent and cell-permeable p38 MAPK inhibitor 152121-30-7. MFCD00941964
Revvity Health Sciences Inc HTRF cAMP Gs HiRange Detection Kit Standard, 10 Vials
HTRF cAMP Gs HiRange Detection Kit Standard, 10 Vials
Akoya Biosciences TSA Cyanine 5 Reagent Pack 50-150 Slides
TSA Cyanine 3 (Cy3) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra Cy5 in the localized area of the probe or antibody.
Abcam Glucose-6-Phosphate Assay Kit (Colorimetric)
Glucose-6-Phosphate Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Aat Bioquest Cal-590™ AM | 5x50ug
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Rhod-2 is most commonly used among the red fluorescent calcium indicators. However, Rhod-2 AM is only moderately fluorescent in live cells upon esterase hydrolysis, and has very small cellular calcium responses. Cal-590™ has been developed to improve Rhod-2 cell loading and calcium response while maintaining the spectral wavelength of Rhod-2, making it compatible with TRITC/Cy3 filter set. In CHO and HEK cells Cal-590™ AM has cellular calcium response that is much more sensitive than Rhod-2 AM.
Meso Scale Discovery Phospho-STAT3 (Tyr705) Kit, 96-well plate, 25 plates, detects STAT3 pTyr705, suitable for human, mouse, rat samples, compatible with various MSD instruments
The MESO SCALE DISCOVERY Phospho-STAT3 (Tyr705) Kit is designed as a rapid and convenient assay for the detection of STAT3 phosphorylated at tyrosine 705. The kit is suitable for research applications focused on phosphoproteins and intracellular signaling across various species, including human, mouse, and rat. Utilizing a 96-well plate format, it enables efficient processing of samples with high-throughput compatibility.
- Detects STAT3 phosphorylated at Tyr705, a crucial activation site.
- Validated for use with human, mouse, and rat samples.
- Compatible with multiple MSD instruments.
- Contains all essential reagents for accurate results.
- Includes comprehensive kit contents such as SULFO-TAG antibody and various buffers.
- Intended for research use only.
- Stored as multi-component modules.
Carnabio Usa Inc CK1G1(CSNK1G1)/5UG/FULL-LENGTH
CK11(CSNK1G1), Full-length, Wild type, Amino Acid 1-422, NP_071331.2, Expressed in Insect (sf21); 5microg
Carnabio Usa Inc CK2A1/B(CSNK2A1/B)/10UG/FULL-L
CK2a1/b(CSNK2A1/B), Full-length(CK2a1), Wild type, Amino Acid 1-391(CK2a1), 1-215(CK2b), NP_001886.1(CK2a1), NP_001311.3(Ck2b1), Expressed in Insect (sf21); 10microg
Enzo Life Sciences Lysophosphatidic acid (25mg). CAS: 325465-93-8
Lysophosphatidic acid (LPA) is a multifunctional intercellular phospholipid messenger. LPA stimulates the growth of a variety of cells including fibroblasts, vascular smooth muscle cells, endothelial cells and keratinocytes. It acts as a proliferative and anti-apoptotic factor. Ligand for LPA1 (EDG-2), LPA2 (EDG-4) and LPA3 (EDG-7) receptors. It also inhibits differentiation of neural stem cells into neurons. Alternative name: 1-Oleoyl-lysophosphatidic acid . sodium salt. Purity: ≥98% (TLC). Solubility: Soluble in water (5 mg/mL with sonication) or DMSO (0.5 mg/mL warm). Long Term Storage: -20°C.
Enzo Life Sciences 8-Bromo-cGMP (10mg). CAS: 51116-01-9
A cell-permeable cGMP analog which is more resistant to phosphodiesterases than cGMP and which preferentially activates cGMP-dependent protein kinase. It inhibits thrombin stimulated arachidonic acid release in human platelets. Purity: ≥96% (HPLC). Solubility: Soluble in water (25mg/ml) or aqueous buffers. Sparingly soluble in methanol (4mM). Insoluble in DMSO, dimethyl formamide and 96% ethanol. Long Term Storage: -20°C.
Medchemexpress LLC Allocryptopine | 485-91-6 | 99.7% | 369.41 g/mol | C21H23NO5 | 10 MG
Allocryptopine is a dibenzazecine alkaloid (C21H23NO5, MW 369.41 g/mol) used as a potassium-channel inhibitor in cardiovascular and ion-channel research. Supplied in small research pack sizes with high reported purity, the compound is intended for in vitro and other laboratory applications as a research reagent.
- Chemical formula: C21H23NO5
- Molecular weight: 369.41 g/mol
- CAS number: 485-91-6
- Purity: 99.7%
- Target: Potassium channel inhibitor (hERG-related activity)
- Intended use: Research use only
- Typical pack size: 10 MG
Enzo Life Sciences SB203580, (1mg), CAS Number: 152121-47-6
Protein kinase inhibitor. Cell permeable, specific inhibitor of p38 (SAPK2a). Inhibits p38 MAPK stimulation of MAPKAPK2 (IC.The concentrations of SB203580 required to block Akt phosphorylation (IC50= 3-5µM) are only approximately 10-fold higher than those required to inhibit p38 MAP kinase (IC50=0.3-0.5µM). These data define a new activity for this drug and suggest that extreme caution should be used when interpreting data when SB203580 has been used at concentrations above 1-2µM. Non-specific effects include inhibition of COX-1 and -2. Enhances clonal growth of skin epithelial progenitor cells and stimulates neural stem cell proliferation. Alternative Name: 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole. Formula: C21H16N3FOS. MW: 377.4. CAS Number: 152121-47-6. Purity: ≥97% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO (50mg/ml). Long Term Storage: -20°C