Signal Transduction Reagents and Kits
Carnabio Usa Inc CK2A1/B(CSNK2A1/B)/5UG/FULL-LE
CK2a1/b(CSNK2A1/B), Full-length(CK2a1), Wild type, Amino Acid 1-391(CK2a1), 1-215(CK2b), NP_001886.1(CK2a1), NP_001311.3(Ck2b1), Expressed in Insect (sf21); 5microg
Carnabio Usa Inc MRCKA(CDC42BPA)/10UG/TRUNCATED
MRCK(CDC42BPA), Truncated protein, Wild type, Amino Acid 1-574, NP_003598.2, Expressed in Insect (sf21); 10microg
Enzo Life Sciences Matrix Metalloproteinase-14 (MMP-14) colorimetric drug discovery kit (1x96wells)
A QUANTIZYME Assay System. The MMP-14 Colorimetric Drug Discovery Kit is a complete assay sytem designed to screen for inhibitors of matrix metalloproteinase-14 (MMP-14, membrane-type matrix metalloproteinase 1, MT1-MMP) using a thiopeptide as a chromogenic substrate. The assays are performed in a convenient 96-well plate format. Also included are active enzyme, a prototypic control inhibitor (NNGH), and a detailed instruction booklet. Alternative name: Membrane type matrix metalloproteinase 1, MT-1 MMP. Applications: Colorimetric detection, HTS Activity assay.
Enzo Life Sciences SB-202190 (1mg). CAS: 152121-30-7
Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis. Alternative name: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole. Purity: ≥98% (TLC). Solubility: Soluble in methanol, DMSO or acetone; slightly soluble in ethyl acetate. Long Term Storage: -20°C.
Enzo Life Sciences ML-7. HCl (10mg). CAS: 109376-83-2
Potent and selective inhibitor of MLC kinase (Ki=0.3 µM). It inhibts also smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA). Alternative name: 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine . HCl. Purity: ≥99%. Solubility: Soluble in DMSO (10mg/ml), ethanol/water (1:1, 10mg/ml), 100% ethanol (warm) and methanol. Long Term Storage: -20°C.
![Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235713.png-250.jpg)
Medchemexpress LLC 3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione | 522649-59-8 | 99.7% | 351.4 g/mol | C20H21N3O3 | 25MG
Malic enzyme inhibitor ME1 is a small-molecule probe that selectively inhibits the cytosolic NADP+-dependent malic enzyme 1 (ME1) with an in vitro IC50 of 0.15 μM. Supplied as a high-purity solid, it is intended for use in biochemical and cell-based studies to interrogate ME1-dependent metabolic pathways and related cellular phenotypes.
- Potent ME1 inhibition (IC50 0.15 μM).
- High purity (≈99.7%).
- Available in multiple vial sizes for scalability.
- Suitable for biochemical and cell-based assays.
- Supports mechanistic studies of metabolism and disease.
Echelon Biosciences Research Labs PI(4,5)P2 PolyPIPosomes 0.25 mL
PolyPIPosomes are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents. PolyPIPosomes are provided as a 1mM total lipid solution containing 5% PIP. Each order of 250 L or 1 mL of PolyPIPosomes includes 100 L of Control PolyPIPosomes. This item is non returnable
Creative Biomart Human F7/Coagulation factor VII human
The product is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
CPC Scientific Ac-Tyr-Val-Lys-Asp-CHO 1MG
Affinity ligand for interleukin-1b converting enzyme. Slow binding caspase-1 (ICE) inhibitor with low selectivity.SEQUENCE: Ac-Tyr-Val-Lys-Asp-CHOONE-LETTER SEQUENCE: Ac-YVKD-CHOMOLECULAR FORMULA: C26H39N5O8MOLECULAR WEIGHT: 549.6STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [147821-01-1]SYNONYMS: RESEARCH AREA: ApoptosisREFERENCES:T.L. Graybill et al., Int. J. Peptide Protein Res., 44, 173 (1994)N.A. Thornbery et al., Nature, 356, 768 (1992)SKU(s): CASP-015A
Enzo Life Sciences (-)-Epigallocatechin gallate (50mg). CAS: 989-51-5
Antitumor reagent. Antioxidant. Protects cells from lipid peroxidation and DNA damage induced by reactive free radicals. Inhibits inducible nitric oxide synthase (iNOS; NOS II). Chemopreventive anticancer agent. Induces apoptosis in human cancer cell lines. Inhibits MAP kinase mediated signalling pathways. Inhibits angiogenesis. Inhibits telomerase and DNA methyltransferase. Anti-inflammatory agent. Alternative name: EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate). Formula: C22H18O11. MW: 458.4. MI: 14: 3526. Purity: ≥98% (HPLC). Solubility: Soluble in 100% ethanol, dimethyl formamide or DMSO; slightly soluble in water. Use/Stability: Stock solutions in DMSO are stable for up to 3 months when stored at -20°C. Long Term Storage: +4°C. Handling: Protect from light. Keep under inert gas. After reconstitution, prepare aliquots and store at -20°C.
Neogen Diagnostics K-Blue Luminescent ONE Substrate, 200 ML, HRP, Microwell, Chemiluminescent
K-Blue Luminescent ONE is a stabilized luminescent substrate for use with horseradish peroxidase immunoassays. It contains both luminol and hydrogen peroxide (H2O2) in a one-bottle format with long-term stability, high sensitivity, and excellent signal to noise. Maximal light emission occurs at 430 nm in the presence of peroxidase labeled conjugate. K-Blue Luminescent ONE is compliant with Annex XVII for REACH and contains no hazardous substances at or above published reporting levels. Stable for a minimum of 12-months when stored at 2-8C.
Abcam Glucose 6 Phosphate Dehydrogenase Activity Assay Kit (Fluorometric)
Glucose 6 Phosphate Dehydrogenase Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement