Signal Transduction Reagents and Kits
Enzo Life Sciences Matrix Metalloproteinase-14 (MMP-14) colorimetric drug discovery kit (1x96wells)
A QUANTIZYME Assay System. The MMP-14 Colorimetric Drug Discovery Kit is a complete assay sytem designed to screen for inhibitors of matrix metalloproteinase-14 (MMP-14, membrane-type matrix metalloproteinase 1, MT1-MMP) using a thiopeptide as a chromogenic substrate. The assays are performed in a convenient 96-well plate format. Also included are active enzyme, a prototypic control inhibitor (NNGH), and a detailed instruction booklet. Alternative name: Membrane type matrix metalloproteinase 1, MT-1 MMP. Applications: Colorimetric detection, HTS Activity assay.
MilliporeSigma BIOLOGY CHEMISCREEN153 MEMB
Life Sciences,Apoptosis & Cell Biology,ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor
Medchemexpress LLC Tulobuterol | 41570-61-0 | MFCD00867022 | 99.7% | 100 MG
Tulobuterol is a long-acting β2-adrenoceptor agonist that helps reduce the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. This sympathomimetic agent is also used as a transdermal patch, increasing normal diaphragm muscle strength. It is intended for research use only.
- Acts as a β2-adrenoceptor agonist
- Reduces RV14 RNA levels and sICAM-1 concentrations in infected cells
- Decreases acidic endosome numbers and fluorescence
- Inhibits RV14 infection-induced secretion of inflammatory cytokines (IL-1β, IL-6, and IL-8)
- Restores and maintains diaphragm muscle contractility
Montana Molecular Green Downward GENIe cGMP Sensor Kit D0800G, 30mL, CMV
Measure cyclic GMP (cGMP) signaling dynamics and ascertain the specificity of PDE inhibitors or SNP activators with this live cell fluorescent assay. Add GENIe to your cells and measure robust signals the next day on an automated plate reader or fluorescence imaging system. Decreasing green fluorescence indicates cGMP increase. The assay is genetically encoded and packaged in BacMam for efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in many primary or iPSC-derived cells. Kit includes soluble guanylate cyclase..
Enzo Life Sciences (2R,4R)-APDC (1mg). CAS: 169209-63-6
Selective agonist for group II mGluRs. Inhibits the NADPH-oxidase dependent ROS system. Alternative name: LY-314,593, (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid. Purity: ≥98% (HPLC). Solubility: Soluble in water. Long Term Storage: Ambient.
Selleck Chemical LLC SB202190 (FHPI) 100mg 152121-30-7
SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38?/? with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1. SB202190 significantly suppresses Erastin?dependent ferroptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Quanterix Inc TSA(TM) FLUORESCEIN SYSTEM (50
TSA, Fluorescein System, for 50-150 Slides. These systems are designed for direct fluorescence detection in ISH or IHC procedures.
CPC Scientific Z-Val-Leu-Leu-CHO 1MG
SEQUENCE: Z-Val-Leu-Leu-CHOONE-LETTER SEQUENCE: ZVLL-CHOMOLECULAR FORMULA: C25H39N3O5MOLECULAR WEIGHT: 461.59STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [263563-09-3]SYNONYMS: -Secretase Inhibitor IIRESEARCH AREA: Alzheimer's DiseaseREFERENCES:G. Abbenante, et al., Biochem. Biophys. Res. Commun. 268, 133 (2000)SKU(s): AMYD-113A
Apexbio Technology LLC D-LUCIF POTASSIUM SALT 500MG
D-LUCIF POTASSIUM SALT 500MG APEXBIO TECHNOLOGIES