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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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The Alkali Scientific Nucleic Acid Maxiprep Purification Column is designed for the efficient extraction and purification of nucleic acids making it an essential tool for molecular biology genetic engineering and diagnostic research This high-performance column enables large-scale purification of DNA and RNA delivering high yields with exceptional purity and consistency Built with a medical-grade six-layer glass fiber membrane this purification column ensures strong binding efficiency structural durability and reliable performance Its advanced filtration system optimizes nucleic acid recovery making it ideal for applications such as PCR qPCR sequencing cloning hybridization and gene expression analysis Six-Layer Filtration High-quality glass fiber membrane enhances nucleic acid binding and purification High Yield and Purity Efficiently isolates large quantities of DNA or RNA with minimal contaminants Large Processing Volume Features a 20 mL purification column for high-throughpu
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5’ triphosphate double-stranded RNA (5’ppp-dsRNA) is a synthetic ligand for the retinoic acid-inducible protein I (RIG-I, also known as Ddx58). RIG-I is a cytoplasmic RNA helicase that belongs to the RIG-I-like receptors (RLRs) family and triggers an antiviral immune response by the activation of type-I interferons (IFN-alpha and -beta).
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