An anticancer compound inhibits proliferation in a panel of melanoma and breast pancreatic and lung cancer cell lines (IC50s 0 674-11 56 M) inhibits migration of and EMT in A375 and B16/F10 melanoma cells in vitro in a concentration-dependent manner reduces the viability of spheroid A375 and B16/F10 cells (IC50s 3 04 and 1 24 M respectively) and increases production of ROS in these cells in a concentration-dependent manner reduces tumor growth in B16/F10 melanoma and Lewis lung carcinoma mouse models and an A375 mouse xenograft model at 5 mg/kg