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Arrays of numerous spots containing specific oligonucleotides, DNA, proteins, peptides or other small molecules chemically attached to a substrate and organized in a grid on a supporting material; probe-based technique used in biochemistry and genetics.
SW1116 [SW 1116, SW-1116] is a cell line exhibiting epithelial morphology that was isolated from the colon of a White, 73-year-old, male patient with colorectal adenocarcinoma. This cell line was deposited by A Leibovitz and can be used in toxicology and cancer research.
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An antiviral agent inhibits SARS-CoV-2 Mpro activity (IC50 0 081 UM) prevents HSV-1 and HSV-2 infection in Vero cells at 0 2 UM inhibits DDAH-1 and HDAC8 (IC50s 9 and 0 011 UM for the human enzymes respectively) inhibits bacterial KDO 8-P synthase (Ki 0 026 UM) reduces endothelial tube formation and LPS-induced NO production in primary human dermal microvascular endothelial cells
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Ubiquitin-K11R is recombinant ubiquitin with a single substitution of arginine for lysine at position 11. Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can subsequently be conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. This modification will ensure chains will not form at mutated lysine to arginine peptide.
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