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Arrays of numerous spots containing specific oligonucleotides, DNA, proteins, peptides or other small molecules chemically attached to a substrate and organized in a grid on a supporting material; probe-based technique used in biochemistry and genetics.
M1-linked ubiquitination is traditionally associated with regulation of NFĸB and IFN signaling. Phospho-ubiquitin chains represent a specialized class of polyubiquitin characterized by phosphorylation at Serine 65 and play a central role in mitophagy signaling pathways. M1 Tetra-Ubiquitin (phosphorylated) is a tetrameric chain of wild-type ubiquitin. It is expressed as a linear chain wherein monomers are linked through N-terminal methionines and C-terminal glycines. The chains are then enzymatically phosphorylated at the Ser65 position.
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PIP Arrays are 4 x 5 cm hydrophobic membranes that have been spotted with a concentration gradient of all eight phosphoinositides. They are used to determine the relative degree of binding of your protein of interest towards one or more of these lipids in a simple protein lipid overlay assay. Bound protein is then detected by an antibody against the protein or affinity tag. This item is non returnable
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NCI-H508 [H508] is a cell line derived from metastasis to the abdominal wall obtained from a patient after treatment with 5-fluorouracil. NCI-H508 [H508] is from the cecum of a White, 55-year-old, male patient with colorectal adenocarcinoma. This cell line was deposited by AF Gazdar.
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