Phosphoramidites
STA PHARMACEUTICAL US LLC STA-AM10021
WuXi TIDES 2'-F C(Ac) amidite - 159414-99-0, 10GR - (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C=C2)NC(C)=O)=O)O[C@@H]1COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)F)OCCC#N)C(C)C)C - M.F. C41H49FN5O8P, M.W. 789.842
STA PHARMACEUTICAL US LLC STA-AM10644
WuXi TIDES 2'-OMe 5-Br-U amidite - 1391914-08-1, 25GR - (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - O=C1C(Br)=CN([C@@H]2O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H]2OC)C(N1)=O - M.F. C40H48BrN4O9P, M.W. 839.721
STA PHARMACEUTICAL US LLC STA-AM10680
WuXi TIDES 2'-F 2-Thio-T amidite - 607353-03-7, 1GR in 60 mL AKTA (Septum) - (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(5-methyl-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N(C(N5)=S)C=C(C5=O)C)F)OCCC#N)C(C)C)C - M.F. C40H48FN4O7PS, M.W. 778.877
Revvity Health Sciences Inc HTRF Human Total JAK2 Detection Kit, 500 Assay Points
HTRF Human Total JAK2 Detection Kit, 500 Assay Points
Cayman Chemical Bz-IEGR-pNAacetate 10mg
A potent autotaxin inhibitor (Ki 15 nM) inhibits production of LPA in mouse rat and human plasma (IC50s 418 542 and 242 nM respectively) reduces extracellular matrix deposition in the lung as well as LPA 182 levels in bronchoalveolar lavage fluid in a mouse model of bleomycin-induced pulmonary fibrosis at 30 mg/kg
Cayman Chemical Bz-IEGR-pNAacetate 25mg
A potent autotaxin inhibitor (Ki 15 nM) inhibits production of LPA in mouse rat and human plasma (IC50s 418 542 and 242 nM respectively) reduces extracellular matrix deposition in the lung as well as LPA 182 levels in bronchoalveolar lavage fluid in a mouse model of bleomycin-induced pulmonary fibrosis at 30 mg/kg
Cayman Chemical 3-Deoxy-3-fluorogunosIn 250mg
An active metabolite of dehydroepiandrosterone formed from dehydroepiandrosterone via 7-hydroxylation by CYPs increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells at 1 UM increases serum concentrations of anti-lysozyme IgG in mice at 6 25 mg/kg
Cayman Chemical I-OMe AG-538 10mg
Immunogen Peptide from the C-terminal region of human c-Kit Host Rabbit Species Reactivity ( ) Human Cross Reactivity ( ) c-Kit Applications IHC WB
Cayman Chemical I-OMe AG-538 25mg
Immunogen Peptide from the C-terminal region of human ALK Host Rabbit Species Reactivity ( ) Human Cross Reactivity ( ) ALK ALK fusion proteins Applications IHC WB
Cayman Chemical 2O 2MethoxyethyladenosIn 250mg
A hydroxyl-terminated PAMAM dendrimer ~45 Å in diameter has 64 surface groups PAMAM G4.0 amidoethanol methylprednisolone conjugates decrease ovalbumin-induced increases in eosinophil numbers in BALF and lung tissue to a greater extent than methylprednisolone alone in a mouse model of lung inflammation toxic to Anabaena and C. reinhardtii (EC90s 5.13 and 1.02 mg/L respectively)
Cayman Chemical 4-deoxy PyrIdoxInhydrochlo 1g
A potent inhibitor of HDAC6 (IC50 0 40 nM) selective for HDAC6 over HDAC3 (IC50 51 61 nM) induces a-tubulin acetylation an HDAC6-dependent process with minimal effect on global lysine acetylation inhibits growth of patient-derived multiple myeloma cell lines (IC50s 1 5-4 7 M) enhances cytotoxicity of bortezomib and carfilzomib against patient-derived multiple myeloma cells decreases tumor size in a human MM 1S multiple myeloma mouse xenograft model when administered in combination with bortezomib at doses of 50 and 0 5 mg/kg respectively