siRNA
ABclonal Technology KO Validated Rab12 MJFF-A-6E6
Rab12 a member of the RAS oncogene family is crucial for intracellular membrane trafficking This small GTPase protein mediates vesicle transport particularly from recycling endosomes to lysosomes playing a key role in autophagy and transferrin receptor degradation Rab12 cycles between inactive GDP-bound and active GTP-bound forms recruiting effectors for vesicle formation movement and fusion It is phosphorylated by LRRK2 which it also regulates Rab12 activates LRRK2 leading to increased phosphorylation of Rab10 aiding in lysosomal function Dysregulation of this pathway especially due to pathogenic LRRK2 mutations may contribute to neurodegenerative processes in Parkinson s disease
ABclonal Technology KO Validated HIF1AN/FIH-1
Enables several functions including 2-oxoglutarate-dependent dioxygenase activity NF-kappaB binding activity and transition metal ion binding activity Involved in several processes including negative regulation of Notch signaling pathway negative regulation of transcription from RNA polymerase II promoter in response to hypoxia and protein hydroxylation Located in cytosol nucleoplasm and perinuclear region of cytoplasm Colocalizes with nucleus
Cell Signaling Technology SignalSilence(R) p21 Waf1/Cip1 siRNA I 300 ul
SignalSilence(R) p21 Waf1/Cip1 siRNA I 300 ul
Cell Signaling Technology PathScanR RP Total PLK1 Sandwich ELISA Kit 20 Kit
PathScanR RP Total PLK1 Sandwich ELISA Kit 20 Kit
Cell Signaling Technology PathScanR RP LC3A Sandwich ELISA Kit 5 Kit
PathScanR RP LC3A Sandwich ELISA Kit 5 Kit
Cell Signaling Technology PathScanR RP Phospho-eIF4E Ser209 Sandwich ELISA Kit 50 Kit
PathScanR RP Phospho-eIF4E Ser209 Sandwich ELISA Kit 50 Kit
Cell Signaling Technology PathScanR RP Total RSK1 Sandwich ELISA Kit 20 Kit
PathScanR RP Total RSK1 Sandwich ELISA Kit 20 Kit
Cell Signaling Technology PathScanR RP Total LRRK2 Sandwich ELISA Kit 20 Kit
PathScanR RP Total LRRK2 Sandwich ELISA Kit 20 Kit
Lonza Walkersville Silensomes CYP3A4 Kit w/Contr
CYP3A4 Silensomes are validated human pooled liver microsomes (HLM) chemically and irreversibly inactivated for CYP3A4 using a mechanism based inhibitor (MBI) Included is a production-matched control HLM
Bioss KD-Validated Carbamoyl-phospha
Carbamoyl-Phosphate Synthase 1 Primary Antibody Unconjugated Public Immunogen Range 100-166/1500 Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Bioss KD-Validated Androgen receptor
Androgen Receptor Primary Antibody Unconjugated Public Immunogen Range 1-61/920 Host Species Rabbit Target Species Human Mouse Clonality Monoclonal Applications WB IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Bioss KD-Validated C1QBP Rabbit Reco
Complement C1q Binding Protein Primary Antibody Unconjugated Public Immunogen Range 200-250/282 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Bioss KD-Validated STAT6 Rabbit Reco
Signal Transducer And Activator Of Transcription 6 Primary Antibody Unconjugated Public Immunogen Range 800-847/847 Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide