siRNA
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS HUMAN MDM2 SIRNA
NC2395929 ON-TARGETPLUS HUMAN MDM2 SIRNA
ABclonal Technology KO Validated Rab12 MJFF-A-6E6
Rab12 a member of the RAS oncogene family is crucial for intracellular membrane trafficking This small GTPase protein mediates vesicle transport particularly from recycling endosomes to lysosomes playing a key role in autophagy and transferrin receptor degradation Rab12 cycles between inactive GDP-bound and active GTP-bound forms recruiting effectors for vesicle formation movement and fusion It is phosphorylated by LRRK2 which it also regulates Rab12 activates LRRK2 leading to increased phosphorylation of Rab10 aiding in lysosomal function Dysregulation of this pathway especially due to pathogenic LRRK2 mutations may contribute to neurodegenerative processes in Parkinson s disease
ABclonal Technology KO Validated SMARCB1/SNF5
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures allowing the transcriptional machinery to access its targets more effectively The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase This gene has been found to be a tumor suppressor and mutations in it have been associated with malignant rhabdoid tumors Alternatively spliced transcript variants have been found for this gene
HORIZON DISCOVERY BIOSCIENCES LIMITED HUMAN FANCM 57697 SIRNA - SM
NC3368668 HUMAN FANCM 57697 SIRNA - SM
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS NON-TARGETING PO
ON-TARGETplus Non-targeting Pool
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLS NON-TRGTNG SIRNA
NC0822648 ON-TARGETPLS NON-TRGTNG SIRNA
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP HU RNF31 SIRNA SMART 20NMO
NC3441417 OTP HU RNF31 SIRNA SMART 20NMO
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS NON-TARGETING
ON-TARGETplus Non-targeting Control siRNAs 50nmol
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP HU SF3B1 SIRNA SP 5NMOL
NC3665130 OTP HU SF3B1 SIRNA SP 5NMOL
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP HU U2AF2 SIRNA SP 5NMOL
NC3665127 OTP HU U2AF2 SIRNA SP 5NMOL
HORIZON DISCOVERY BIOSCIENCES LIMITED Accell Green Non-targeting Control siRNA, 20nmol
Accell Green Non-targeting Control siRNA provides qualitative assessment of Accell siRNA uptake as determined by fluorescent microscopy to evaluate cytoplamic localization of the dye-labeled Accell siRNA or FACS analysis to determine general uptake. Non-targeting siRNA reagents are designed to aid in the interpretation of experiments with Accell siRNA reagents as highly reliable controls for assessment of baseline cellular responses.
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS CYCLOPHILIN B
ON-TARGETplus Cyclophilin B Control siRNA (Mouse) 5nmol
HORIZON DISCOVERY BIOSCIENCES LIMITED ONTRGTPLUS HMN FAP 2191 5NMOL
NC3851845 ONTRGTPLUS HMN FAP 2191 5NMOL