Bioactive Small Molecules
Apexbio Technology LLC GSK 650394, 5mg. Cas: 890842-28-1 MFCD: MFCD12828779. SGK1 inhibitor
GSK 650394 is a small molecule inhibitor of serum and glucocorticoid-regulated kinase 1 (SGK1) with IC50 value of 13nM [1].Sgk1 gene is a target gene of androgen. Knockdown of SGK1 expression attenuates androgen-mediated growth of the prostate cancer cell line. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC AZD6482, 5mg. Cas: 1173900-33-8 MFCD: MFCD16659062. PI3Kβ inhibitor,potent and selective
AZD6428 is a potent, selective and ATP-competitive PI3K inhibitor. IC50 are 0.69, 13.6, 47.8 and 136 nM for PI 3-K, PI 3-K, PI 3-K and PI 3-K, respectively. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC SGI-1776 free base, 10mg. Cas: 1025065-69-3 MFCD: MFCD16659064. Pim kinase inhibitor,ATP-competitive
SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival. Other sizes are available. Please inqury us for quote.
STEMCELL Technologies CFTR(inh)-172, Size: 5 mg
CFTR(inh)-172 is a selective and reversible thiazolidinone inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR; Ki = 300 nM; Ma et al.). CFTR is a chloride anion channel involved in the secretion of fluid in many epithelial tissues, such as the airway and intestine (Ma et al.). Defects in the CFTR gene alter ion transport, which can lead to cystic fibrosis (Dalli et al.; Ma et al.). When it is intraperitoneally injected in mice, CFTR(inh)-172 inhibits the secretion of intestinal fluid induced by cholera toxin (Ma et al.).DISEASE MODELING· Slows cyst growth in polycystic kidney disease in mice (Yang et al.).
Apexbio Technology LLC Olaparib (AZD2281, Ku-0059436), 500mg. Cas: 763113-22-0 MFCD: MFCD13185161. Potent PARP1/PARP2 inhibitor
Olaparib (4-(3-4-fluorophenyl) methyl-1(2H)-one), as known as AZD2281 or KU0059436, is a novel, selective and potent inhibitor of both poly adenosine diphosphate-ribose polymeras-1 (PARP-1) and poly adenosine diphosphate-ribose polymeras-2 (PARP-2). Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC Mildronate, 50mg. Cas: 76144-81-5 MFCD: MFCD00876389. GBB hydroxylase inhibitor
Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC GSK126, 100mg. Cas: 1346574-57-9 MFCD: MFCD23381067. EZH2 inhibitor
GSK126 is an inhibitor of EZH2 with Ki Value of 93 pM [1].Over-expression of EZH2 has been reported to be correlated with cancer progression and poor prognosis, high grade and high stage in several tumor types. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC R428, 10mg. Cas: 1037624-75-1 MFCD: MFCD21608463. Selective Axl inhibitor
R428 is a selective Axl inhibitor with an IC50 of 14 nM, more than 50-fold sensitivity for Axl than Abl, Mer, Tyro3, InsR, EGFR, HER2, and PDGFR. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC Cilengitide, 10mg. Cas: 188968-51-6 MFCD: MFCD04307743. Integrin inhibitor for αvβ3 and αvβ5
Cilengitide is a cyclic RGD pentapeptide [Arg-Gly-Asp-DPhe-(NMeVal)], and a potent v3 and v5 integrin inhibitor to block integrin-mediated adhesion and migration. It can directly bind v3 integrin. Its IC50 is 250 nM as an v3 inhibitor [1] [2] [3] [4]. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC Levonorgestrel, 50mg. Cas: 797-63-7 MFCD: MFCD00199013. Estrogen/progestogen receptor agonist
Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Other sizes are available. Please inqury us for quote.
Medchemexpress LLC Sodium tripolyphosphate | 7758-29-4 | MFCD00003514 | 98.2% | 367.86 g/mol | Na5P3O10 | 25 MG
Sodium tripolyphosphate (STPP), 98% is a white to off-white solid biochemical reagent used for pH adjustment, metal ion chelation, and as a detergent additive. It has molecular formula Na5P3O10 and a molecular weight of 367.86 g/mol; packaged in small quantities for laboratory use and recommended for cold storage to maintain stability.
- High purity (98.23%) for reproducible results.
- Functions as a pH adjustment agent and chelating agent.
- Useful as a detergent additive and formulation aid.
- Solid, white to off-white form for easy handling.
- Available in small pack sizes suitable for laboratory research.
- Store powder at -20°C for long-term stability.
Medchemexpress LLC Triflumizole | 68694-11-1 | >=90.0% - <=100.0% | 345.75 g/mol | C15H15ClF3N3O | 25 MG
Triflumizole is an imidazole-class fungicide that inhibits ergosterol biosynthesis and is used to control powdery mildew and scab on a variety of fruits and agricultural crops. The substance has the chemical formula C15H15ClF3N3O and a molecular weight of 345.75 g/mol. It is supplied both as technical material and in formulated crop-protection products; concentration varies by formulation. Follow the product safety data sheet for handling, storage, and regulatory guidance.
- Inhibits ergosterol biosynthesis in fungal pathogens.
- Effective control of powdery mildew and scab on fruits and crops.
- Available as technical grade and in formulated products with varying active concentrations.
- Chemical formula C15H15ClF3N3O; molecular weight 345.75 g/mol.
- Refer to the safety data sheet for handling, storage, and personal protective equipment.
![Medchemexpress LLC Hexaammineruthenium(II) chloride | 15305-72-3 | MFCD00011477 | 98.0% | 274.16 g/mol | [Ru(NH3)6]Cl2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000303135.png-250.jpg)
Medchemexpress LLC Hexaammineruthenium(II) chloride | 15305-72-3 | MFCD00011477 | 98.0% | 274.16 g/mol | [Ru(NH3)6]Cl2 | 25 MG
Hexaammineruthenium(II) chloride is the inorganic salt [Ru(NH3)6]Cl2 commonly used as a research reagent and as a redox and fluorescent probe in laboratory studies. It is provided as a solid powder with typical high purity and defined storage recommendations for long-term stability.
- Chemical formula: [Ru(NH3)6]Cl2.
- Molecular weight: 274.16 g/mol (reported values may vary by source).
- Purity: 98% typical for listed product specifications.
- Form: powder; store at -20°C for long term or 4°C for shorter storage.
- Common applications: redox chemistry, electrochemical studies, fluorescence labeling.
Medchemexpress LLC Anthraquinone-2-carboxylic acid | 117-78-2 | MFCD00001231 | 98.0% | 252.22 g/mol | C15H8O4 | 1 ML
Anthraquinone-2-carboxylic acid is an anthraquinone derivative isolated from Brazilian taheebo with reported anti-inflammatory and antinociceptive activity. It is supplied for research use in powder form or as a 10 mM solution in DMSO, and is intended for in vitro applications when handled and stored per recommended conditions.
- CAS number 117-78-2.
- Purity 98.0%.
- Molecular formula C15H8O4; molecular weight 252.22 g/mol.
- Available as powder and as a 10 mM solution in DMSO (1 mL).
- Soluble in DMSO at 25 mg/mL (≈99.12 mM); ultrasonic assistance recommended.
- Powder storage: -20°C (3 years) or 4°C (2 years).
- In-solvent storage: -80°C (6 months) or -20°C (1 month).
- For research use only.
Medchemexpress LLC 2'-(4-methylumbelliferyl)-alpha-d-n-acetylneuraminic acid sodium salt | 76204-02-9 | 98.1% | 489.41 g/mol | C21H24NNaO11 | 25 MG
4-MUNANA is a fluorogenic substrate used to quantify neuraminidase (sialidase) activity in biochemical and cell-based assays. As the sodium salt of 2'-(4-methylumbelliferyl)-α-D-N-acetylneuraminic acid, enzymatic cleavage releases the fluorescent 4-methylumbelliferone reporter for sensitive fluorometric detection.
- Fluorogenic substrate for neuraminidase assays (excitation ~365 nm; emission ~410 nm).
- Releases 4-methylumbelliferone upon enzymatic hydrolysis for sensitive detection.
- High purity suitable for research use (98.08%).
- Solid, white to light yellow; molecular weight 489.41 g/mol.
- Stable when stored sealed at -20°C; in solvent: -80°C (6 months), -20°C (1 month).
- Available in small research pack sizes for laboratory assays.