Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1
Tocris Bioscience™ Yoda 1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Piezo1 channel activator
| Target | Other Calcium Channel Activators |
|---|---|
| CAS | 448947-81-7 |
| Purity | >99% |
| Chemical Name or Material | 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C13H8Cl2N4S2 |
| Formula Weight | 355.27 |
2
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Invitrogen™ BODIPY™ 493/503 (4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene)
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Invitrogen™ BODIPY™ 493/503 (4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene)
BODIPY™ 493/503 can be used as a stain for neutral lipds, and as a tracer for oil and other nonpolar lipids.
Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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3
| CAS | 29767-20-2 |
|---|---|
| Molecular Formula | C32H32O13S |
4
| CAS | 259793-96-9 |
|---|---|
| Molecular Formula | C5H4FN3O2 |
5
| CAS | 6902-77-8 |
|---|---|
| Molecular Formula | C11H14O5 |
6
Invitrogen™ Bis-ANS (4,4'-Dianilino-1,1'-Binaphthyl-5,5'-Disulfonic Acid, Dipotassium Salt)
Binds with affinity that is often orders-of-magnitude higher than 1-8-ANS as probe for nonpolar cavities in proteins
Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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7
Tocris Bioscience™ SJF 1521
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective EGFR PROTAC™
8
Tocris Bioscience™ A 83-01
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A 83-01 synthesized to Ancillary Material Grade
9
Tocris Bioscience™ AM 580
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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AM 580 synthesized to Ancillary Material Grade
10
Tocris Bioscience™ Tissue Clearing Pro
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Tissue clearing reagent kit
11
Tocris Bioscience™ P7C3
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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NAMPT Activators
| CAS | 301353-96-8 |
|---|---|
| Chemical Name or Material | 3,6-Dibromo-α-[(phenylamino)methyl]-9H-carbazole-9-ethanol |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C21H18Br2N2O |
| Formula Weight | Observed MW: 474.19 |
| Assay Percent Range | >99% |
12
Tocris Bioscience™ AS 1842856
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective Foxo1 inhibitor; orally bioavailable
| CAS | 836620-48-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Molecular Formula | C18H22FN3O3 |
13
Tocris Bioscience™ KY 02111
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
| CAS | 1118807-13-8 |
|---|---|
| Chemical Name or Material | N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H17ClN2O3S |
| Formula Weight | Observed MW: 376.86 |
| Assay Percent Range | >99% |
14
Tocris Bioscience™ A 412997 dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective D4 agonist
| CAS | 1347744-96-0 |
|---|---|
| Chemical Name or Material | N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C19H23N3O.2HCl |
| Formula Weight | Observed MW: 382.33 |
| Assay Percent Range | >98% |
15
Tocris Bioscience™ Vancomycin HCl
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Antibiotic