Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical ANTIBODY GalactItol 250g
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A reduced form of galactose; a toxic metabolite of galactose in humans; accumulates in the lens of patients with galactokinase deficiency-induced galactosemia, leading to cataract formation; accumulates in a transgenic mouse model of galactokinase deficiency but does not lead to cataract formation
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Abcam Nipecotic acid (mM/ml), GABA reuptake inhibitor, 100MM_ML
MW 129.16 Da, Purity >98%. GABA reuptake inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
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AdipoGen A-443654 (5 mg)
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Chemical. CAS: 552325-16-3. Formula: C24H23N5O. MW: 397.5. Synthetic. Potent and selective Akt inhibitor (Ki=160pmol/L for all three isoforms PKBalpha, PKBbeta and PKBgamma). DYRK1A inhibitor (IC50=10nM). Inhibits other kinases, including PRK2, MSK1 and DYRK3 at low nM range as well. Interferes with mitotic progression by regulating aurora a kinase expression and bipolar spindle formation. It induces G2/M accumulation, defects in centrosome separation and formation of either monopolar arrays or disorganized spindles. Anticancer agent. Apoptosis inducer and chemosensitizing agent. Slows the progression and growth of Akt-dependent tumors. Induces rapid Akt Ser473 phosphorylation independent of mTORC1 inhibition in human cancer cell lines. Activates mTORC2 and reverses long-term memory deficits.
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eMolecules 937272-79-2 | Medchem Express | Pacritinib | 5mg | 446267397 | HY-16379 | 472.589 | C28H32N4O3
Medchem Express | Pacritinib | 5mg | 446267397 | HY-16379 | 937272-79-2 | 472.589 | C28H32N4O3
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eMolecules 185351-19-3 | Medchem Express | NQTrp | 5mg | 719836244 | HY-19738 | MFCD21496345 | 360.369 | C21H16N2O4
ChemScene | 7-Amino-4-methyl-1H-indole-3-carbonitrile | 100mg | 536802978 | CS-0096448 | 289483-87-0 | MFCD09955317 | 171.203 | C10H9N3
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eMolecules 1811510-56-1 | Medchem Express | PF-06260933 | 5mg | 446269959 | HY-19562 | 296.76 | C16H13ClN4
Medchem Express | NRX-2663 | 5mg | 713706630 | HY-141448 | 2763260-34-8 | 418.328 | C20H13F3N2O5
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![Medchemexpress LLC (7S)-3-fluoro-4-[3-(8-fluoro-1-methyl-2,4-dioxoquinazolin-3-yl)-2-methylphenyl]-7-(2-hydroxypropan... | 1643368-58-4 | 99.4% | 572.60 g·mol⁻¹ | C32H30F2N4O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248081.png-250.jpg)
Medchemexpress LLC (7S)-3-fluoro-4-[3-(8-fluoro-1-methyl-2,4-dioxoquinazolin-3-yl)-2-methylphenyl]-7-(2-hydroxypropan... | 1643368-58-4 | 99.4% | 572.60 g·mol⁻¹ | C32H30F2N4O4 | 25 MG
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BMS-986142 is a potent, highly selective, reversible small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with reported IC50 ≈ 0.5 nM. It is supplied as a high-purity research reagent (powder) for preclinical and translational studies; molecular formula C32H30F2N4O4 and CAS 1643368-58-4.
- Potent reversible BTK inhibition (IC50 ≈ 0.5 nM).
- High selectivity across kinase panels to reduce off-target effects.
- High purity suitable for biochemical and cellular assays.
- Stable powder form with defined storage conditions for long-term use.
- Suitable for preclinical pharmacology and mechanistic studies.
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Enzo Life Sciences Propidium Iodide (ultra pure) (100mg). CAS: 25535-16-4
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Propidium iodide (PI) belongs to the same chemical class as ethidium bromide. As with ethidium bromide, its fluorescence is enhanced 20-30-fold upon binding to nucleic acids. The fluorescence excitation maximum is red-shifted 30-40 nm and the fluorescence emission maximum blueshifted ~15 nm. PI also binds to RNA as does DAPI and acridine orange. PI is membrane impermeant and is commonly used for identifying dead cells in a mixed population of cells and as a counter-stain in multicolor fluorescent techniques. It can also be used to differentiate necrotic, apoptotic and viable cells. The dye is suitable for fluorescence microscopy, flow cytometry and fluorometry applications. Wavelength Maxima: Excitation 535nm, Emission 617nm Purity: ≥95% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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Cayman Chemical PF-04979064 10mg
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A dual inhibitor of PI3K and mTOR (Kis = 0.13, 0.111, 0.122, and 1.42 nM for PI3Kα, PI3Kγ, PI3Kδ, and mTOR, respectively); selective for PI3K and mTOR over a panel of 36 other kinases at 1 µM; inhibits phosphorylation of Akt in BT-20 cells (IC50 = 9.1 nM); reduces tumor volume by 88% in a U87MG glioblastoma mouse xenograft model at 40 mg/kg; increases alveolar epithelial cell apoptosis in a mouse model of COPD induced by PM2.5
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Medchemexpress LLC DL-Tryptophan | 54-12-6 | 99.98% | 204.23 | 10 G
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DL-Tryptophan is an endogenous metabolite.
- Appearance: Solid
- Color: White to light yellow
- Shipping: Room temperature in continental US
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
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Cayman Chemical -CloprostenolsodIum salt 5mg
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(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol.
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Cayman Chemical 10 11-Cl-BBQ 5mg
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A mixture of 10-Cl-BBQ and 11-Cl-BBQ that acts as an AhR agonist; induces Cyp1a1 transcription in mouse liver at 10 mg/kg
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Medchemexpress LLC HY-13306 5mg Medchemexpress, Pyrintegrin CAS:1228445-38-2 Purity:>98%
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Medchemexpress, HY-13306 5mg Pyrintegrin CAS:1228445-38-2 Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival. Pyrintegrin enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling. Pyrintegrin can be used as a podocyte-protective agent and has robustly adipogenic[2][3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Cayman Chemical DrImentIn A 5mg
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A terpenylated diketopiperazine
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Selleck Chemical LLC Ripretinib S8757-25MG
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Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) Kit (c-Kit) and PDGFR-alpha with IC50 values of 4 nM 8 nM 18 nM 5 nM and 14 nM for WT Kit (c-Kit) V654A Kit (c-Kit) T670I Kit (c-Kit) D816H Kit (c-Kit) and D816V Kit (c-Kit) respectively
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