Bioactive Small Molecules
Medchemexpress LLC 3-desacetyl cefotaxime lactone | 66340-33-8 | MFCD24386610 | 97.0% | C14H13N5O5S2 | 10MG
3-Desacetyl cefotaxime lactone (CAS 66340-33-8) is the lactone form of the active metabolite of the third-generation cephalosporin antibiotic cefotaxime. It is provided as a white to off-white solid and is intended for use as an analytical reference standard, impurity characterization, and metabolic or degradation studies in pharmaceutical research.
- High purity (97.0%) suitable for analytical applications.
- White to off-white solid, amenable to standard handling and storage.
- Useful as an impurity and metabolite standard for cephalosporin studies.
- Supplied in small-mass quantities appropriate for reference use.
- Supports structural characterization and stability testing.
Cayman Chemical ANTIBODY CP 775 146 10mg
A PPARα agonist; binds selectively to PPARα (Ki = 24.5 nM) over PPARβ and PPARγ (Kis = >10,000 nM); induces PPARα transcriptional activity in a reporter assay (EC50s = 57 and 284 nM for human and rat receptors, respectively, expressed in HepG2 cells); decreases plasma triglyceride levels in mice by 73% at 2 mg/kg per day for two days
Cayman Chemical ANTIBODY LIpId A9 50mg
An ionizable cationic lipid (pKa = 6.27); has been used in the generation of LNPs for the delivery of mRNA and siRNA in vivo; LNPs containing lipid A9 and encapsulating non-stimulatory siRNA increase plasma levels of CCL2, indicating activation of the innate immune response, and decrease body weight in mice
eMolecules 2249106-01-0 | Medchem Express | SN-008 | 5mg | 705861051 | HY-145009 | 446.5 | C25H19FN2O3S
Ambeed | 2-(3-Fluoro-5-methylphenyl)acetic acid | 250mg | 521477510 | A729396 | 518070-22-9 | MFCD03094318 | 168.167 | C9H9FO2
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Medchemexpress LLC VE-Cadherin Human 50ug
The FGFR-4 protein binds to its ligands and activates signaling pathways involved in cell growth differentiation and survival It plays a role in various developmental processes including skeletal development liver metabolism and cancer progression In the absence of ligand binding FGFR-4 remains inactive and does not initiate downstream signaling cascades VE-Cadherin Protein Human (HEK293 C-His-Fc) is the recombinant human-derived VE-Cadherin protein expressed by HEK293 with C-hFc C-6 His labeled tag
Cayman Chemical ANTIBODY XMD16-5 5mg
A TNK2 inhibitor (IC50 = 0.38 µM); decreases viability of Ba/F3 cells expressing the oncogenic TNK2 D163E and R806Q mutant proteins (IC50s = 16 and 77 nM, respectively)
Cayman Chemical CephacetrIle 5mg
A cephalosporin antibiotic; active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, and Klebsiella (MICs = 0.64, 0.64, 0.16, 6.25 and 3.12 UG/ml, respectively); active against veterinary isolates of S. aureus from bovine mastitis at 30 UG/disc
Medchemexpress LLC Anti-Rabbit IgG for 50uL | 50uL
Anti-Rabbit IgG for IP (HRP) is a conformation-specific secondary antibody that binds exclusively to native non-denatured IgG and does not recognize denatured IgG Conformation-specific secondary antibodies target spatial epitopes When antibodies are denatured by high temperatures they lose their native conformation and are no longer recognized by such antibodies neither the heavy chain nor the light chain is detected This effectively avoids interference from the heavy chain (55 kDa) and light chain (25 kDa) in immunoprecipitation (IP) experiments
Cayman Chemical McaSEVNLDAEFRK DnpRRNH2 5mg
A fluorogenic substrate for BACE; Mca is released upon cleavage by BACE and its fluorescence can be used to quantify BACE activity; ex/em = 328/420 nm, respectively
Selleck Chemical LLC H 33258 trihydrochloride E2910-5MG
bisBenzimide H 33258 Trihydrochloride(Hoechst 33258 trihydrochloride H 33258 trihydrochloride) is a marker dye in Hoechst series Hoechst is A live nuclear marker dye It binds to the grooves in the DNA double strand which tends to be A/ T-rich DNA strand Although it binds to all nucleic acids the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore Hoechst dye can be used for living cell labeling The fluorescence intensity of Hoechst dye increases with the increase of pH of solution It exhibits anti-tumor activity IC50 of 51 31 4 56 M in HeLa cells
Cayman Chemical ANTIBODY DB07268 1mg
A potent inhibitor of JNK1 (IC50 = 9 nM); binds to the ATP site of JNK1; selective for JNK1 over P38, ERK2, AKT1, CHK1, and PAK4 among others
Cayman Chemical ANTIBODY nI 9 5mg
An inhibitor of ANO1 that blocks ATP-induced apical membrane chloride currents in ANO1-expressing FRT cells (IC50 = 77 nM); selective for ANO1 over ANO2 at 10 μM and CFTR and ENaC at 30 μM; inhibits ATP-induced quenching of a fluorescent intracellular halide sensor in PC3 prostate cancer cells and Capan-1 pancreatic carcinoma cells in a concentration-dependent manner
Medchemexpress LLC HY-B2233B 500mg Medchemexpress, Phosphorylcholine CAS:3616-04-4 Purity:>98%
Medchemexpress, HY-B2233B 500mg Phosphorylcholine CAS:3616-04-4 Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.