Bioactive Small Molecules
Cayman Chemical ANTIBODY L-LeucIn 100g
An essential amino acid; increases basal insulin secretion and decreases glucose-induced insulin release in INS-1E cells at 1, 5, and 10 mM; decreases triglyceride levels and increases cholesterol accumulation in INS-1E cells at 1, 5, and 10 mM; stimulates skeletal muscle protein synthesis in food-deprived or exercised rats
Medchemexpress LLC FGF-1 Mouse 1mg
Recombinant mouse fibroblast growth factor-1 supplied as a lyophilized, tag-free protein for in vitro studies of cell proliferation, angiogenesis, and signaling. The preparation is validated for purity and bioactivity and is intended for use in cell-based assays requiring biologically active FGF-1.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Lyophilized powder for long-term stability and convenient storage.
- Tag free to minimize interference in binding or signaling assays.
- Predicted molecular mass ~15.8 kDa; observed ~18 kDa by SDS-PAGE.
- High specific activity (ED50 ≈ 1-2 ng/mL in fibroblast proliferation assays).
- Stable at -20°C; reconstituted material stable short term at 4°C.
Cayman Chemical ANTIBODY Gn-6640 25mg
An inhibitor of USP7 (IC50 = 0.75 µM); selective for USP7 over USP47 and USP5 (IC50s = 20.3 and >200 µM, respectively); enhances ubiquitination of the USP7 substrate MDM2 in HCT116 colon cancer cells (IC50 = 0.23 µM); reduces cell viability in a panel of 108 cell lines (IC50s = <10 µM for all); enhances apoptosis induced by doxorubicin or cisplatin in MCF-7 and U2OS cancer cells, respectively
Medchemexpress LLC L-AP4 monohydrate | 2247534-79-6 | 99.0% | 201.11 g/mol | C4H12NO6P | 10 MG
L-AP4 monohydrate is a selective agonist of group III metabotropic glutamate receptors used in pharmacological and biochemical research to probe mGlu4, mGlu8, mGlu6, and mGlu7 signaling. It is supplied as a monohydrate solid suitable for in vitro studies.
- Selective group III metabotropic glutamate receptor agonist.
- Reported EC50s: mGlu4 0.13 μM; mGlu8 0.29 μM; mGlu6 1.0 μM; mGlu7 249 μM.
- High purity (99.0%) for research applications.
- Molecular weight 201.11 g/mol; formula C4H12NO6P.
- Soluble in DMSO (~10 mg/mL; may require sonication).
- Recommended storage sealed, away from moisture and light; solids at 4°C; in solution -80°C up to 6 months.
Cayman Chemical ANTIBODY V-9302 25mg
An inhibitor of ASCT2; inhibits glutamine uptake (IC50s = 9 and 9.6 µM for the rat and human transporters, respectively); reduces cell viability of a variety of cancer cell lines, including HCT116, HT-29, COLO 205, and RKO cells (EC50s = 8.9, 9.4, 14.5, and 8.3 µM, respectively); reduces glutamine uptake into tumor tissue and prevents tumor growth in HCT116 and HT-29 mouse xenograft models expressing K-RasG13D and BRAFV600E mutations, respectively, at 75 mg/kg per day for 21 days
Medchemexpress LLC HY-N3009 20mg Medchemexpress, Secoxyloganin CAS:58822-47-2 Purity:>98%
Medchemexpress, HY-N3009 20mg Secoxyloganin CAS:58822-47-2 Secoxyloganin, isolated from Lonicera japonica Thunb, inhibits the blood flow (BF) decrease. Secoxyloganin has allergy-preventive activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10957 5mg Medchemexpress, L-692429 CAS:145455-23-8 Purity:>98%
Medchemexpress, HY-10957 5mg L-692429 CAS:145455-23-8 L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 binds to G protein-coupled receptor with a Ki of 63 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N3733 5mg Medchemexpress, Deoxylapachol CAS:3568-90-9 Purity:>98%
Medchemexpress, HY-N3733 5mg Deoxylapachol CAS:3568-90-9 Deoxylapachol is a major cytotoxic component of New Zealand brown alga, Landsburgia quercifolia. Deoxylapachol has antifungal and anti-cancer activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-109068A 5mg Medchemexpress, Parsaclisib (hydrochloride) CAS:1995889-48-9 Purity:>98%
Medchemexpress, HY-109068A 5mg Parsaclisib (hydrochloride) CAS:1995889-48-9 Parsaclisib hydrochloride (INCB050465 hydrochloride) is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0331A 500mg Medchemexpress, Enalapril (maleate) CAS:76095-16-4 Purity:>98%
Medchemexpress, HY-B0331A 500mg Enalapril (maleate) CAS:76095-16-4 Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0287 500mg Medchemexpress, Clofibrate CAS:637-07-0 Purity:>98%
Medchemexpress, HY-B0287 500mg Clofibrate CAS:637-07-0 Clofibrate is an agonist of PPAR, with EC50s of 50 μM, ∼500 μM for murine PPARα and PPARγ, and 55 μM, ∼500 μM for human PPARα and PPARγ, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical 5-chloro-2-ThIothInonhydro 5mg
An analytical reference that is structurally similar to known stimulants; intended for research and forensic applications