Bioactive Small Molecules
![Medchemexpress LLC Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[[[5-(2-thienyl... | 1186206-79-0 | 99.01% | 607.69 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386814-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[[[5-(2-thienyl... | 1186206-79-0 | 99.01% | 607.69 | 100 MG
ALW-II-41-27 is an Eph family tyrosine kinase inhibitor with an IC50 of 11 nM for Eph2. This compound is suitable for research applications targeting tyrosine kinases.
- Inhibits Ba/F3 cells transformed with Tel fusions of EphA3, Kit, Fms, KDR, FLT1, FGR, Src, Lyn, Bmx, and Bcr-Abl.
- Exhibits cross-reactivity with Bcr-Abl.
- Inhibits a broad range of kinases including b-raf, CSF1R, DDR1, DDR2, EphA2, EphA5, EphA8, EphB1, EphB2, EphB3, Frk, Kit, Lck, p38α, p38β, PDGFRα, PDGFRβ, and Raf1.
Cayman Chemical ANTIBODY Vedaprofen 5mg
An NSAID commonly used in veterinary medicine to combat pain, inflammation, and fever; blocks the activity of the E. coli DNA polymerase III β subunit, preventing DNA replication and repair
TARGETMOL CHEMICALS INC ETIPREDNOL DICLOACETATE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Etiprednol dicloacetate (BNP-166) is a corticosteroid with anti-inflammatory activity.Etiprednol dicloacetate inhibits the accumulation of eosinophils and can be used in the study of inflammatory airway diseases such as asthma and in the treatment of Crohn's disease. purity: 99%
Cayman Chemical ANTIBODY ASP3026 10mg
An ALK inhibitor (IC50s = 3.5, 10, and 5.4 nM for the wild-type, ALKF1174L, and ALKR1275Q enzymes, respectively); selective for ALK over a panel of 86 kinases at 1,000 nM but also inhibits ROS1 and TNK2 (IC50s = 8.9 and 5.8 nM, respectively); inhibits the proliferation of Ba/F3 cells expressing NPM-ALK or ELM4-ALK fusion proteins (IC50s = 84 and 56 nM, respectively), as well as several crizotinib-resistant Ba/F3 cells expressing NPM-ALK or ELM4-ALK mutants; induces tumor regression in an NCI H2228 NSCLC mouse xenograft model at 10 and 30 mg/kg
Medchemexpress LLC Mito-DK | 95.1% | 608.49 | 50 MG
Mito-DK is a small-molecule fluorescent dye that offers crosstalk-free response to polarity and mtDNA, as well as mitochondrial morphology. It exhibits high photostability, low cytotoxicity, and good mitochondria-targeting properties. It can be used for real-time tracking and multidimensional assessment of mitochondria-related pyroptosis in cancer cells.
- Small-molecule fluorescent dye
- Crosstalk-free response to polarity and mtDNA
- Crosstalk-free response to mitochondrial morphology
- High photostability
- Low cytotoxicity
- Good mitochondria-targeting properties
- Can be used for real-time tracking and multidimensional assessing of mitochondria-related pyroptosis in cancer cells
Cayman Chemical FTY720 phenoxy-bIotIn 100ug
A biotin-tagged analog of FTY720; methanol side chain of FTY720 that is targeted for phosphorylation by sphingosine kinases is retained, suggesting that it would likewise be phosphorylated in vivo
Cayman Chemical ANTIBODY PolygodIal 1mg
A sesquiterpene dialdehyde noted for its broad antifungal properties; cytotoxic against bacteria, algae, and sea squirts; in mammals, produces a pungent flavor, activates TRPA1 (EC50 = 59 nM), and produces antinociception
World Precision Instrument GSNO S-nitrosoglutatione-GSNO-50
GSNO has been identified in vivo as a potential storage and transport vehicle for NO in the body. GSNO has been used in clinical trials to treat a form of preeclampsia and to prevent platelet aggregation. It also has considerable potential as NO donor in medicine.
Medchemexpress LLC Ceefourin 1 | 315702-40-0 | MFCD02329957 | 294.42 g·mol⁻¹ | C11H10N4S3 | 100 MG
Ceefourin 1 is a potent, selective inhibitor of multidrug resistance protein 4 (MRP4/ABCC4) supplied for research and analytical applications. It is used in transporter assays and cell-based studies to probe MRP4-mediated efflux and as a chemosensitizer probe in preclinical research. The compound has formula C11H10N4S3 and a molecular weight of 294.42 g·mol⁻¹.
- Selective MRP4 inhibitor for transporter studies.
- Useful as an analytical standard for assay development and validation.
- Reported low cellular toxicity in standard assays.
- Soluble in DMSO, suitable for in vitro use.
- Available as a small-quantity powder for research applications.
Cayman Chemical DehydrotumulosIc AcId 5mg
A triterpene with anticancer and anti-inflammatory activities; enhances vincristine-induced cytotoxicity against multidrug-resistant KBv200 cells at 12.5 or 25 UG/ml; reduces serotonin-induced hind paw edema, as well as TPA-induced EAr edema, in mice at 50 mg/kg
Medchemexpress LLC EGFR Rat HEK293 H 2ug
EGFR Protein is a receptor tyrosine kinase that binds to ligands of the EGF family EGFR Protein is involved in the regulation of NF-kappa-B RAS-RAF-MEK-ERK PI3 kinase-AKT PLCgamma-PKC and STATs signaling pathways EGFR Protein has calmodulin binding activity epidermal growth factor binding activity and epidermal growth factor activating receptor activity EGFR Protein Rat (HEK293 His) is the recombinant rat-derived EGFR protein expressed by HEK293 with C-His labeled tag
STA PHARMACEUTICAL US LLC 1-DMTr-2-(S)-propanediyl amidite | 1 g | CAS 161029-25-0 | InChIKey XCLJWHBPKOARSH-VNFCCXQASA-N
1-DMTr-2-(S)-propanediyl amidite is a Amidite reagent (Subcategory: Spacer Modifiers) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. Ships on dry ice. SDS available for reference.
Specifications
- CAS: 161029-25-0
- MDL: No data
- InChIKey: XCLJWHBPKOARSH-VNFCCXQASA-N
- Molecular Weight: 578.689761998
- Molecular Formula: C33H43N2O5P
- Purity: ≥95%
- Container Type: 60 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 63 g
- Commodity Code: 29299090
- Country Of Origin: China
- IUPAC: (S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: C[C@@H](COC(C1=CC=C(OC)C=C1)(C2=CC=CC=C2)C3=CC=C(OC)C=C3)OP(N(C(C)C)C(C)C)OCCC#N
Enzo Life Sciences Ac-VDVAD-pNA (5mg). CAS: 189684-53-5
Chromogenic substrate for caspase-2. Preferred substrate for caspase-2 (Km=53μM) Alternative name: Caspase 2 substrate (chromogenic). Formula: C29H41N7O12. MW: 679.7. Purity: ≥98% (HPLC). Formulation: Lyophilized. Solubility: Soluble in DMSO (100mM). Dilute stock solution with distilled water or buffer. Long Term Storage: -20°C.
Selleck Chemical LLC L-Arginine E4831-1G
L-Arginine (L-glutamate) (Arginine glutamate) is a mixture of amino acids that induces apoptosis via hypertonic stress It also promotes gastric relaxation by providing L-arginine for nitric oxide production thereby benefiting gastrointestinal motility and conditions associated with vagus nerve dysfunction