Crosslinking, Labeling and Protein Modification
eMolecules CBZ-aminooxy-PEG8-t-butyl ester | Broadpharm |647.759 | C31H53NO13 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCONC(=O)OCc1ccccc1 | 500mg | 550804549
CBZ-aminooxy-PEG8-t-butyl ester | Broadpharm |647.759 | C31H53NO13 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCONC(=O)OCc1ccccc1 | 500mg | 550804549
Medchemexpress LLC m-PEG4-Hydrazide | 1449390-68-4 | >98% | C10H22N2O5 | 250 MG
m-PEG4-Hydrazide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker, with one ligand for an E3 ubiquitin ligase and the other for the target protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only and not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- For research use only
Medchemexpress LLC 1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane | 55400-73-2 | 95.0% | 350.41 | 1 G
Ms-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Cayman Chemical DMPE-MPEG 2000 250mg
An oligosaccharide comprised of nine a-14-linked glucose molecules has been used as a substrate to study the cleavage distribution and enzyme kinetics of B. licheniformis thermostable a-amylase as well as the enzyme kinetics of A. niger glucoamylase II
Medchemexpress LLC (S,R,S)-AHPC-PEG3-N3 | 1797406-80-4 | MFCD31807299 | >95.0% | 645.77 g/mol | C30H43N7O7S | 500 MG
(S,R,S)-AHPC-PEG3-N3 is a VHL (E3 ligase) ligand-linker conjugate bearing a terminal azide (-N3) for copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is used as a building block for PROTACs and bifunctional probes, enabling VHL recruitment and modular conjugation via click chemistry.
- E3 ligase (VHL) ligand-linker conjugate suitable for PROTAC design.
- Terminal azide enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Three-unit PEG linker provides flexibility and spacing between ligand and cargo.
- Useful as a building block for bifunctional molecules and bioconjugation.
- Reported appearance: solid-liquid mixture; CAS 1797406-80-4; molecular weight 645.77 g/mol.
Medchemexpress LLC DBCO-PEG4-DBCO | 2182601-68-7 | 97.4% | 250 MG
DBCO-PEG4-DBCO is a versatile PEG-based PROTAC linker and a cleavable ADC linker. It is utilized in the synthesis of PROTACs and antibody-drug conjugates (ADCs). This compound functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.
- Used in PROTAC synthesis
- Cleavable ADC linker
- Click chemistry reagent
- Features a DBCO group
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with azide groups
Cayman Chemical ANTIBODY DBCO acId 500mg
A copper-free click chemistry reagent; has been used in the study of glycoprotein charge effects on the migration and invasion of 9-azido sialic acid-labeled cancer cells in vitro; has also been used in the synthesis of DBCO-modified RNase A to deliver RNase A into AAM-labeled cancer cells in vitro and in vivo to induce cytotoxicity and reduce tumor growth, respectively
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG8-CH2COOH | 25 g | CAS 868594-52-9 | MDL MFCD27635163
Fmoc-NH-PEG8-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 868594-52-9
- MDL: MFCD27635163
- InChIKey: JRLUSGRARXJCNA-UHFFFAOYSA-N
- Molecular Weight: 649.734
- Molecular Formula: C33H47NO12
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azatriacontan-30-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
eMolecules 557756-85-1 | Fmoc-PEG4-Propionic acid | AA Blocks LLC | MFCD06656472 | 487.549 | C26H33NO8 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 410171202
Fmoc-PEG4-Propionic acid | AA Blocks LLC | 557756-85-1 | MFCD06656472 | 487.549 | C26H33NO8 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 410171202
Medchemexpress LLC Azide-PEG-amine | 00-00-0 | 95.0% | N3-PEG-NH2 (polymeric, avg. MW 2000) | 10MG
Azide-PEG-amine (average MW 2000) is a bifunctional polyethylene glycol linker with an azide group and a primary amine, supplied as a white to off-white solid. It is intended for click chemistry and conjugation workflows, enabling both copper-catalyzed and strain-promoted azide-alkyne cycloadditions for linker assembly, PEGylation, and bioconjugation applications.
- Bifunctional azide and amine termini for orthogonal conjugation.
- Average molecular weight 2000 for flexible spacer properties.
- High purity (95.0%) suitable for research-grade conjugation reactions.
- White to off-white solid for easy handling.
- Stable under recommended storage conditions to preserve activity.
Medchemexpress LLC Ald-Ph-amido-PEG4-C2-NHS ester | 1353011-74-1 | 98.1% | 494.49 g/mol | C23H30N2O10 | 250 MG
A noncleavable 4-unit PEG linker bearing an NHS ester reactive group for antibody-agent conjugation. It is supplied for research use and is amine-reactive for coupling payloads to antibody lysines.
- Noncleavable 4-unit PEG spacer provides hydrophilicity and flexibility.
- NHS ester functionality for amine-reactive conjugation.
- High purity suitable for research applications.
- Soluble in DMSO; protocols provided for in vivo formulations.
- Stable when stored pure at -20°C.
Cayman Chemical CLS-MPEG 2000 100mg
A PEGylated form of cholesterol; has been used in the synthesis of liposomes for targeted drug delivery
Medchemexpress LLC 5,8,11,14-tetraoxa-2-azahexadecanedioic acid, 1-(1,1-dimethylethyl) ester | 876345-13-0 | MFCD30528568 | 97.0% | 351.39 | C15H29NO8 | 500 MG
Boc-NH-PEG4-CH2COOH is a Boc-protected PEG4 linker with a terminal carboxylic acid, intended for use as a cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker in medicinal chemistry and bioconjugation research.
- Boc-protected amino group for orthogonal protection
- Four-unit polyethylene glycol spacer for improved solubility and flexibility
- Terminal carboxylic acid for amide coupling or conjugation
- High purity suitable for research applications
- Stable under recommended storage conditions
![eMolecules 7-O-(Bromoacetamido-PEG4)- paclitaxel | Broadpharm |1222.142 | C60H73BrN2O20 | 95.000 | CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C3[C@@]4(CO[C@@H]4C[C@H](OC(=O)CCOCCOCCOCCOCCNC(=O)CBr)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c1ccccc1)c1ccccc1 | 10mg ...](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183502.JPG-250.jpg)
eMolecules 7-O-(Bromoacetamido-PEG4)- paclitaxel | Broadpharm |1222.142 | C60H73BrN2O20 | 95.000 | CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C3[C@@]4(CO[C@@H]4C[C@H](OC(=O)CCOCCOCCOCCOCCNC(=O)CBr)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c1ccccc1)c1ccccc1 | 10mg ...
7-O-(Bromoacetamido-PEG4)- paclitaxel | Broadpharm |1222.142 | C60H73BrN2O20 | 95.000 | CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C3[C@@]4(CO[C@@H]4C[C@H](OC(=O)CCOCCOCCOCCOCCNC(=O)CBr)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c1ccccc1)c1ccccc1 | 10mg | 550804560