Protein Labeling Reagents
Biotium CD5(Cris-1), CF568 conjugate, 0.1mg/mL
Recognizes a 67 kDa transmembrane protein, which is identified as CD5 (HLDA I; WS Code T 29HLDA III; WS Code T 530). The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Human Kappa Light Chain(L1C1), CF568 conjugate, 0.1mg/mL
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can gi
Biotium CD28(204.12), CF568 conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
eMolecules 25535-16-4 | Medchem Express | Propidium (Iodide) | 10mg | 446274299 | HY-D0815 | MFCD00011921 | 668.406 | C27H34I2N4
Medchem Express | W-7 (hydrochloride) | 25mg | 536983735 | HY-100912 | 61714-27-0 | MFCD00012559 | 377.320 | C16H22Cl2N2O2S
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Biotium Fascin-1(FSCN1/418), CF488A conjugate, 0.1mg/mL
Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection o
Biotium CD28(C28/74), CF568 conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Medchemexpress LLC CalFluor 488 Azide | 1798305-98-2 | C37H49N5O13S2 | 1 MG
CalFluor 488 Azide is a water-soluble fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reactions. It remains non-fluorescent until it reacts with alkynes, making it ideal for specific applications. The azide group allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules or ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Water-soluble fluorogenic azide probe
- Activated by Cu-catalyzed or metal-free click reactions
- Non-fluorescent until reaction with alkynes
- Capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Capable of ring strain-promoted alkyne-azide cycloaddition (SPAAC)
- Used for biological conjugation and label coupling
- Categorized as a fluorescent dye and azide reactive dye for click chemistry
![eMolecules Broadpharm / BP Fluor 488 Maleimide / 1mg / 591908398 / BP-25506 / 97.000 / / [null] / 720.660 / C30H25N4NaO12S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502472385.JPG-250.jpg)
eMolecules Broadpharm / BP Fluor 488 Maleimide / 1mg / 591908398 / BP-25506 / 97.000 / / [null] / 720.660 / C30H25N4NaO12S2
Broadpharm / BP Fluor 488 Maleimide / 1mg / 591908398 / BP-25506 / 97.000 / / [null] / 720.660 / C30H25N4NaO12S2
(=O)=O)c3ccc(cc3C2(C)CCCCCC(=O)ON2C(=O)CCC2=O)S(O)(=O)=O)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 599128647](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502464411.JPG-250.jpg)
eMolecules 407627-68-3 | BP Fluor 555 NHS ester | Broadpharm930.040 | C38H47N3O16S4 | 0.000 | CC1(C)\C(=C/C=C/C2=[N+](CCCS([O-])(=O)=O)c3ccc(cc3C2(C)CCCCCC(=O)ON2C(=O)CCC2=O)S(O)(=O)=O)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 599128647
BP Fluor 555 NHS ester | Broadpharm | 407627-68-3930.040 | C38H47N3O16S4 | 0.000 | CC1(C)\C(=C/C=C/C2=[N+](CCCS([O-])(=O)=O)c3ccc(cc3C2(C)CCCCCC(=O)ON2C(=O)CCC2=O)S(O)(=O)=O)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 599128647
eMolecules Carboxyrhodamine 110-PEG3-Azide | 1536327-95-3 | | 100mg
Broadpharm | Carboxyrhodamine 110-PEG3-Azide | 100mg | 268505038 | BP-22478 | 95.000 | 1536327-95-3 | | 574.594 | C29H30N6O7
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![eMolecules 197306-80-2 | BDP TR X NHS ester | Broadpharm634.460 | C31H29BF2N4O6S | 0.000 | F[B-]1(F)n2c(ccc2-c2ccc(OCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)cc2)C=C2C=CC(c3cccs3)=[N+]12 | 1mg | 761705583](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502459511.PNG-250.jpg)
eMolecules 197306-80-2 | BDP TR X NHS ester | Broadpharm634.460 | C31H29BF2N4O6S | 0.000 | F[B-]1(F)n2c(ccc2-c2ccc(OCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)cc2)C=C2C=CC(c3cccs3)=[N+]12 | 1mg | 761705583
BDP TR X NHS ester | Broadpharm | 197306-80-2634.460 | C31H29BF2N4O6S | 0.000 | F[B-]1(F)n2c(ccc2-c2ccc(OCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)cc2)C=C2C=CC(c3cccs3)=[N+]12 | 1mg | 761705583
Biotium IGF-1(M23), CF568 conjugate, 0.1mg/mL
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific
Medchemexpress LLC HY-100335 50mg Medchemexpress, PCI-33380 CAS:1022899-36-0 Purity:>98%
Medchemexpress, HY-100335 50mg PCI-33380 CAS:1022899-36-0 PCI-33380 is an irreversible Bruton's Tyrosine Kinase (BTK) inhibitor (fluorescent probe). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Biotium CD26(202-36), CF488A conjugate, 0.1mg/mL
Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405