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Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.
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Search Within Results
Keyword Search:
331 – 345 of 5,607 results
331

Medchemexpress LLC WIZ DEGRADER 8 5 mg
SDP

WIZ DEGRADER 8 5MG

ENCOMPASS_PREFERRED
332

Medchemexpress LLC PROTAC TBK1 DEGRADER 1 mg
SDP

PROTAC TBK1 DEGRADER 1MG

ENCOMPASS_PREFERRED
333

Medchemexpress LLC PROTAC HDAC DEGRADER 5 mg
SDP

PROTAC HDAC DEGRADER 5MG

ENCOMPASS_PREFERRED
334

Medchemexpress LLC PROTAC EGFR DEGRADER 1 mg
SDP

PROTAC EGFR DEGRADER 1MG

ENCOMPASS_PREFERRED
335

Sigma Aldrich Fine Chemicals Biosciences GUANIDINE HYDROCHLORIDE 5KG

NC3886657 GUANIDINE HYDROCHLORIDE 5KG

ENCOMPASS
336

Medchemexpress LLC MEDCHEMEXPRESS LLC
SDP

NC3988720 PROTAC SMARCA2 DEGRADER-8 1MG

ENCOMPASS
337

Syd Lab Inc SYD LAB INC

NC3990090 DBET1 5MG

ENCOMPASS
338

Syd Lab Inc SYD LAB INC

NC3990092 DBET1 10MG

ENCOMPASS
339

Medchemexpress LLC Protac Cbp/P300 Degrader-1 25M | HY-138536-25MG
SDP

Protac Cbp/P300 Degrader-1 25M

ENCOMPASS_PREFERRED
340

Medchemexpress LLC PROTAC EGFR degrader 4 | 2882845-50-1 | 99.7% | 995.29 | 1 MG
SDP

PROTAC EGFR degrader 4 is a potent PROTAC targeting mutant EGFR. It induces degradation of EGFRdel19 and EGFRL858R/T790M with DC50s of 0.51 and 126 nM, respectively. The compound significantly inhibits the growth of HCC827 and H1975 cell lines with IC50s of 0.83 and 203.1 nM, respectively. The induced EGFR degradation is associated with autophagy.

  • Displays excellent activity of inducing EGFRdel19 degradation with a DC50 value of 0.51 nM.
  • Dramatically reduces the phosphorylation of EGFR and its downstream effector Akt in HCC827 and H1975 cell lines.
  • Induces HCC827 cell line to undergo apoptosis at concentrations of 10 and 100 nM.
  • Arrests both HCC827 and H1975 cell lines at G1 phase.

ENCOMPASS_PREFERRED
341

Cambridge Isotope Laboratories GUANIDINE:HBR (15N3, 98%), 0.1 G

GUANIDINE:HBR (15N3, 98%), 0.1 G

ENCOMPASS
342

Medchemexpress LLC Protac Egfr Degrader 7 1Mg | HY-147858-1MG
SDP

Protac Egfr Degrader 7 1Mg

ENCOMPASS_PREFERRED
343

eMolecules​ 28821-35-4 | PEG16 | Broadpharm | MFCD29079393 | 678.810 | C30H62O16 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 298819268

PEG16 | Broadpharm | 28821-35-4 | MFCD29079393 | 678.810 | C30H62O16 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 298819268

ENCOMPASS_PREFERRED
344

eMolecules​ PLGA(5k)-PEG(3k)-PLGA(5k) | Broadpharm |322.266 | C12H18O10 | 0.000 | [H]OC(C)C(=O)OCC(=O)OCCOC(=O)COC(=O)C(C)O[H] | 500mg | 686680814

PLGA(5k)-PEG(3k)-PLGA(5k) | Broadpharm |322.266 | C12H18O10 | 0.000 | [H]OC(C)C(=O)OCC(=O)OCCOC(=O)COC(=O)C(C)O[H] | 500mg | 686680814

ENCOMPASS_PREFERRED
345

eMolecules​ Methyltetrazine-PEG23-DBCO | Broadpharm |1531.796 | C76H118N6O26 | 95.000 | Cc1nnc(nn1)-c1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCC(=O)N2Cc3ccccc3C#Cc3ccccc23)cc1 | 25mg | 698442881

Methyltetrazine-PEG23-DBCO | Broadpharm |1531.796 | C76H118N6O26 | 95.000 | Cc1nnc(nn1)-c1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCC(=O)N2Cc3ccccc3C#Cc3ccccc23)cc1 | 25mg | 698442881

ENCOMPASS_PREFERRED