Protein Modification Reagents
Medchemexpress LLC Dope-peg-mal | 98.2% | 2000 Da | 5 MG
DOPE-PEG-Mal (MW 2000) is a maleimide-functionalized dioleoyl phosphoethanolamine-polyethylene glycol conjugate formulated for liposome and nanoparticle preparation and for covalent attachment to thiol-containing ligands. The maleimide group enables rapid, selective thiol coupling under mild conditions to yield stable thioether linkages; the PEG moiety (average MW ~2000 Da) provides steric stabilization in formulations.
- Maleimide-functionalized lipid for thiol conjugation.
- Selective thiol reactivity at pH 6.5-7.5 forming stable thioether bonds.
- Suitable for liposome and nanoparticle formulation.
- Average PEG molecular weight ~2000 Da for steric stabilization.
- High reported purity (≈98.2%).
- Available in small research pack sizes for formulation work.
eMolecules Fmoc-PEG24-NHS ester | | | 500mg
Broadpharm | Fmoc-PEG24-NHS ester | 500mg | 550804596 | BP-24349 | 98.000 | | | 1465.682 | C70H116N2O30
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eMolecules PC-Biotin-PEG4 | | | 250mg
Broadpharm | PC-Biotin-PEG4 | 250mg | 528284366 | BP-24517 | 98.000 | | | 669.790 | C30H47N5O10S
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Biotium TCEP
TCEP (Tris(2-carboxyethyl)phosphine) hydrochloride is an odorless reducing agent that is more stable and effective than dithiothreitol (DTT) or 2-Mercaptoethanol. TCEP hydrochloride is soluble in water to 310 grams per liter. Unlike DTT, TCEP hydrochloride retains its reducing power at acid pH (pH 5) and at pH above 7.5. TCEP hydrochloride is unreactive towards other functional groups found in proteins. For reducing disulfide bonds in peptides or proteins, 5-50 mM TCEP can be used for a few minutes at room temperature.Properties: C9H15O6P HCl; Mwt: 286.64; [51805-45-9].
Cayman Chemical DL-DIthIothreItol 1g
A reducing agent; has been used to stabilize thiols in a reduced state in various applications, including protein purification and enzymatic assays
AdipoGen TCEP (5 g)
Chemical. CAS: 51805-45-9. Formula: C9H15O6P·HCl. MW: 286.60. TCEP is an odorless, selective, and water-soluble strong reducing agent that is commonly used in biochemistry and molecular biology applications. It is commonly used to rapidly reduce protein and peptide disulfide bonds a preparatory step for gel electrophoresis. TCEP can be combined with proteases to simultaneously reduce and digest proteins prior to mass spectrometry in order to dramatically increase sequence coverage. More stable than DTT and useful in mass spectrometry applications. It has also been used to measure ascorbic acid and dehydroascorbic acid in biological samples. TCEP is a useful chelating agent for various heavy metal ions as Zn(II), Cd(II), Pb(II), and Ni(II).
Crescent Chemical Co Inc MERCAPTOETHANOL MOL BIO GRADE
Mercaptoethanol molecular biology grade DNase/RNase not detected. Size - 50ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 39563.01 CAS 60-24-2
Sigma Aldrich Fine Chemicals Biosciences DL-Dithiothreitol, 3483-12-3, MFCD00004877, 1 G
Linear Formula: HSCH2CH(OH)CH(OH)CH2SH, Molecular Weight: 154.25, ≥98% (HPLC), ≥99.0% (titration), Synonym: threo-1,4-Dimercapto-2,3-butanediol, Cleland’s reagent, DTT. An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides.
Enzo Life Sciences DTT (5g). CAS: 3483-12-3
Cell permeable protective agent for SH groups, maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. ER-stress inducer. Alternative name: 1,4-Dithio-DL-threitol, DL-Dithiothreitol, Cleland's Reagent. Purity: ≥98% (Assay by Iodometric Titration). Solubility: Soluble in water, 100% ethanol, acetone or ethyl acetate. Long Term Storage: +4°C.
Ubpbio TCEP Powder, 25 GR, CAS# 51805-45-9
Reducing Agents - TCEP - TCEP (tris(2-carboxyethyl)phosphine) is a strong reducing agent. Compared to dithiothreitol (DTT) and β-mercaptoethanol, TCEP has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. It is soluble in water and stable at neutral pH. It does not reduce metals used in immobilized metal affinity chromatography such as Ni-NTA resin. TCEP is particularly useful when labeling cysteine residues with maleimides.
eMolecules Sulfo DBCO-PEG4-amine | 2055198-05-3 | MFCD30458045 | 500mg
Broadpharm | Sulfo DBCO-PEG4-amine | 500mg | 340377136 | BP-23310 | 95.000 | 2055198-05-3 | MFCD30458045 | 674.770 | C32H42N4O10S
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Medchemexpress LLC Me-tet-peg4-cooh | 2141976-30-7 | 98.7% | 477.51 g·mol⁻¹ | C22H31N5O7 | 10 MG
Me-Tet-PEG4-COOH is an ADC linker containing four polyethylene glycol (PEG) units and a tetrazine group that enables inverse electron demand Diels-Alder (iEDDA) bioorthogonal conjugation with TCO-containing partners. Intended for research use in bioconjugation and ADC development.
- Purity: 98.68%
- Molecular weight: 477.51 g·mol⁻¹
- Chemical formula: C22H31N5O7
- Cas number: 2141976-30-7
- Appearance: pale purple to purple solid
- Solubility: DMSO 125 mg/mL (requires ultrasonic; use newly opened DMSO)
- Storage: powder -20°C up to 3 years; in solvent -80°C for 6 months, -20°C for 1 month
- Product type: ADC linker
AG Scientific Inc PEG 8000, 1 KG
PEG 8000 (Polyethylene Glycol) is ultra-pure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.CAS Number: 25322-68-3Molecular Weight: 7,000-9,000 DaSolubility: WaterStorage Temperature: Room TemperatureResearch or further manufacturing use only, not for food or drug use.CAS Number: 25322-68-3Molecular Weight: 7,000-9,000 DaSolubility: WaterStorage Temperature: Room TemperatureShipping Weight: 0.0626 lbsResearch or further manufacturing use only, not for food or drug use.
Medchemexpress LLC HY-112599 500mg Medchemexpress, Pomalidomide-PEG4-C2-NH2 CAS:2225940-52-1 Purity:>98%
Medchemexpress, HY-112599 500mg Pomalidomide-PEG4-C2-NH2 CAS:2225940-52-1 Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.