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Reporter genes are attached to a regulatory sequence of a gene of interest. When expressed by the host organism, they generate measurable, easily identifiable characteristics that can be used as an indication of whether a gene has been taken up or expressed.
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA VEGFB and PGF and plays an essential role in the development of embryonic vasculature the regulation of angiogenesis cell survival cell migration macrophage function chemotaxis and cancer cell invasion The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis
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Enables platelet-derived growth factor-activated receptor activity and signaling receptor binding activity Involved in several processes including positive regulation of intracellular signal transduction protein phosphorylation and vasculature development Acts upstream of or within several processes including animal organ development response to ceramide and ruffle assembly Located in cell surface cytoplasm and ruffle Is expressed in several structures including alimentary system extraembryonic component genitourinary system nervous system and sensory organ Used to study basal ganglia calcification infantile myofibromatosis myeloproliferative neoplasm and severe nonproliferative diabetic retinopathy Human ortholog(s) of this gene implicated in basal ganglia calcification glioblastoma infantile myofibromatosis myeloproliferative neoplasm (multiple) and renal cell carcinoma Orthologous to human PDGFRB (platelet derived growth factor receptor beta)
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