Immunohistochemistry Kits and Reagents
Abcam TripleStain IHC Kit: M&R&G on human tissue (DAB, AP/Red & HRP/Green), 18ML
Abcam's TripleStain IHC Kit (ab183290) is designed to be used with user-supplied one goat, one mouse and one rabbit primary antibodies to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical p38 MAPK InhIbItr IV 25mg
An ATP-competitive inhibitor of p38 MAPKs; inhibits p38α, p38β, p38��, and p38δ MAPKs (IC50s = 0.13, 0.55, 5.47, and 8.63 μM, respectively); inhibits LPS-induced TNF-α and IL-1β cytokine production in human peripheral blood mononuclear cells (IC50s = 22 and 44 nM, respectively)
Biocare Medical, LLC Immunocare TBS Wash Buffer, 10X
Immunocare TBS Wash Buffer (sodium azide and thimerasol free) works well for manual and automated immunohistochemistry applications as well as other laboratory procedures requiring a high quality TBS buffer with superior pH stability. The buffer contains surfactant and allows for reagents to spread more uniformly across tissue sections on slides. It has been specifically formulated with Enzyme Activator for Alkaline Phosphatase detection systems. It can also be used on an automated staining system.
Biotium Human Kappa Light Chain(L1C1), CF594 conjugate, 0.1mg/mL
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can gi
Biocare Medical, LLC MACH 2 Double Stain 2 - 25 ml
The conjugated goat anti-mouse polymer horseradish peroxidase (HRP) and the conjugated goat anti-rabbit polymer alkaline phosphatase (AP) secondary antibodies react with both heavy and light chains on mouse and rabbit IgG respectively. This innovative HRP- and AP-polymerization technology provides a significant increase in staining sensitivity when compared to other conventional HRP- or AP-conjugated secondary antibodies. Avidin-biotin blocking procedures are not necessary when using the MACH 2 conjugated secondary antibodies. It is specially designed for a rapid double stain procedure. An antibody cocktail with a mouse monoclonal and a rabbit polyclonal/monoclonal must be used. The overall staining procedure can be done with 4 major steps and in less than two hours. It can be used manually or used with automated stainers.
Meso Scale Discovery RPLEX MSE Periostin/OSF2 ASYQP
The R-PLEX Mouse Periostin (OSF-2) Assay from Meso Scale Discovery is a multiplex immunoassay that measures periostin (OSF-2) in mouse samples such as serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescence (ECL) detection technology and provides high sensitivity a wide dynamic range and requires a low sample volume The assay can be fully automated and has a rapid 2 5 hour turnaround time It is available as a singleplex assay that measures only periostin or as a multiplex assay that measures periostin along with other analytes This assay allows the quantitative measurement of periostin which plays a role in cardiac remodeling and bone metabolism
Biotium CD4(C4/206), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 55 kDa, identified as CD4. CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
ABclonal Technology NDUFA4L2 Rabbit pAb
Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex IV.
Enzo Life Sciences HIGHDEF red IHC chromogen (AP, plus) (30 ml)
High definition IHC chromogen producing brilliant red color for AP-activated development in automated and manual systems. HIGHDEF red IHC chromogen (AP, plus) is intended to be used in conjuction with alkaline phosphatase (AP)-based immunostaining or in situ hybridization systems that run on automated staining instruments as well as manual use. Contents: HIGHDEF red IHC chromogen (AP, plus) substrate buffer and chromogen, Empty mixing bottle. Application: IHC, ISH (in situ hybridization). Long Term Storage: +4°C
Biotium CD6(3F7B5), CF594 conjugate, 0.1mg/mL
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD147(8D6), CF594 conjugate, 0.1mg/mL
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium HIF1α(HIF1A-84), CF594 conjugate, 0.1mg/mL
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc.) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains stab
STEMCELL Technologies MegaCult™-C Staining Kit for CFU-Mk, Size: 1 Kit
Stain fixed and dehydrated CFU-Mk colonies cultured in MegaCult™-C collagen-based medium using the reagents included in MegaCult™-C Staining Kit for CFU-Mk. • MegaCult™-C Primary Antibody• MegaCult™-C Control Antibody• MegaCult™-C Human Serum• MegaCult™-C Alkaline Phosphatase Substrate Tablets• MegaCult™-C Biotin-Conjugated Goat Anti-Mouse IgG• MegaCult™-C Evans Blue Stain• MegaCult™-C 10% BSAMegakaryocytes and platelets expressing the glycoprotein IIb/IIIa are stained with anti-human CD41 antibody and an alkaline phosphatase detection system. The kit is also suitable for the detection of bipotential erythroid-megakaryocyte progenitor cells (BFU-E/Mk).For your convenience, the kit components are also available for purchase individually, upon request.
Cell Signaling Technology SignalStain(R) Boost IHC Detection Reagent (HRP, Goat) 15 ml
SignalStain(R) Boost IHC Detection Reagent (HRP, Goat) 15 ml