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Fully sequenced samples of complimentary DNA synthesized from single-stranded, mammalian RNA. Various gene inserts sourced from humans, mice, monkeys, and other species are available. Ideal for use in gene cloning, as gene probes, and in cDNA library creation.
Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions
Both IL-12 R subunit extracellular domains are composed of three fibronectin-like domains and two cytokine receptor homology domains. IL-12R beta 2 also has an extracellular Ig-like domain
Studies suggest a correlation between the levels of CD25/IL-2 R alpha in serum with the onset of rejection in allograft recipients, with autoimmune disease activation in rheumatoid arthritis and systemic lupus erythematosis patients and with the course of some leukemias and lymphomas
IL9R is expressed in T cells, neutrophils, mast cells, and macrophages. It may be associated with the development of asthma. Alternatively splices transcripts encoding different proteins have been described