Amino Acid Analysis Reagents and Accessories
Apexbio Technology LLC Parathyroid Hormone (1-34), bovine 12583-68-5 5mg
Parathyroid hormone (PTH) is a polypeptide hormone secreted from parathyroid chief cells involved primarily in calcium and phosphate homeostasis The bioactive sequence of the bovine PTH fragment (1-34) retains essential biological activity and specifically interacts with parathyroid hormone receptors (PTHR) predominantly PTHR1 expressed in bone and kidney tissues enhancing calcium ion reabsorption and promoting bone resorption PTH (1-34) peptide acts through G protein-coupled signaling pathways increasing cyclic AMP (cAMP) production thereby regulating extracellular calcium concentrations Due to its defined molecular action bovine PTH (1-34) serves as a valuable research tool in biochemical pharmacological and bone metabolism studies including osteoporosis research and calcium regulation experiments
Enzo Life Sciences LYSO-ID Green detection kit (2x96wells)
The LYSO-ID Green detection kit contains an acidic organelle-selective dye suitable for live-cell staining. Conventional fluorescent stains for acidic organelles, such as Acridine Orange (ENZ-52405), form metachromatic artifacts that interfere with multicolor imaging applications. LYSO-ID Green dye generates emission profiles that can be multiplexed with other fluorophores. The dye accumulates in acidic compartments, such as endosomes, lysosomes, and secretory vesicles. Low micromolar concentrations of LYSO-ID Green dye are sufficient for staining mammalian cells. This has been validated with the human cervical carcinoma cell line, HeLa, the human T-lymphocyte cell line, Jurkat, and the human bone osteosarcoma epithelial cell line, U2OS. The LYSO-ID Green dye is a new green-emitting, cell-permeable small organic probe molecule that spontaneously localizes to live cell acidic organelles. Applications: Fluorescence microscopy, Fluorescent detection .