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Apexbio Technology LLC Parathyroid Hormone (1-34), bovine 12583-68-5 5mg
Supplier: Apexbio Technology LLC A11145
Parathyroid hormone (PTH) is a polypeptide hormone secreted from parathyroid chief cells involved primarily in calcium and phosphate homeostasis The bioactive sequence of the bovine PTH fragment (1-34) retains essential biological activity and specifically interacts with parathyroid hormone receptors (PTHR) predominantly PTHR1 expressed in bone and kidney tissues enhancing calcium ion reabsorption and promoting bone resorption PTH (1-34) peptide acts through G protein-coupled signaling pathways increasing cyclic AMP (cAMP) production thereby regulating extracellular calcium concentrations Due to its defined molecular action bovine PTH (1-34) serves as a valuable research tool in biochemical pharmacological and bone metabolism studies including osteoporosis research and calcium regulation experiments
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