Toxins
Medchemexpress LLC Cholera toxin B subunit, from vibrio cholerae | 131096-89-4 | 95.0% | 1 MG
Cholera toxin B subunit, from vibrio cholerae (CTB) is non-toxic to cells and lacks intrinsic adenylate cyclase activity. It attaches to cells by binding to ganglioside GM1. CTB is recognized as an effective tracer for studying axonal transport and is widely used as a marker for membrane lipid rafts.
- Attaches to cells by binding to ganglioside GM1
- Suitable label for microglial cells
- Effective tracer for studying axonal transport using immunohistochemical methods
- Widely used as a marker of membrane lipid rafts
- Inhibits the production of TNFα in E. coli
Sigma Aldrich Fine Chemicals Biosciences Cucurbitacin E-2-O-glucoside phyproof(R) Reference Substance | 1398-78-3 | MFCD00046215 | 10MG
Cucurbitacin E-2-O-glucoside phyproof(R) Reference Substance | Purity: >=98.0% (HPLC) | Mol Wt: 718.83 | 1398-78-3 | MFCD00046215 | 10MG
Medchemexpress LLC HY-13062 50mg Medchemexpress, Daunorubicin (Hydrochloride) CAS:23541-50-6 Purity:>98%
Medchemexpress, HY-13062 50mg Daunorubicin (Hydrochloride) CAS:23541-50-6 Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) is a topoisomerase II inhibitor with potent antineoplastic activities. Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) inhibites DNA and RNA synthesis in sensitive and resistant Ehrlich ascites tumor cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical CytochalasIn D 10mg
A cell-permeable inhibitor that binds actin filaments, but not actin monomers, to inhibit polymerization at concentrations as low as 0.2 µM
Medchemexpress LLC HY-N0021 10mg Medchemexpress, Verbascoside CAS:61276-17-3 Purity:>98%
Medchemexpress, HY-N0021 10mg Verbascoside CAS:61276-17-3 Verbascoside is isolated from Lantana camara, acts as an ATP-competitive inhibitor of PKC , with an IC 50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Immunochemistry Technology Nigericin 0.5 µmoles, 25 -50 test size
Nigericin is a potent microbial toxin that acts as a potassium ionophore, inducing a net decrease in intracellular levels of potassium. This is critical for the oligomerization of the NLRP3 inflammasome and activation of caspase-1 in pyroptosis. Nigericin can be used as a positive control in pyroptosis experiments.
eMolecules 471-95-4 | Medchem Express | Bufotalin | 5mg | 446275489 | HY-N0878 | MFCD00210248 | 444.568 | C26H36O6
Ambeed | 15-Diphenyl-1H-pyrazole-4-carboxylic acid | 100mg | 525203112 | A390609 | 98700-53-9 | MFCD02186759 | 264.284 | C16H12N2O2
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![eMolecules 66584-72-3 | Ansamitocin P 3 | Broadpharm635.150 | C32H43ClN2O9CO[C@@H]1C=CC=C(C)Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)C(C)C)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2 | 25mg | 704981316](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502463320.JPG-250.jpg)
eMolecules 66584-72-3 | Ansamitocin P 3 | Broadpharm635.150 | C32H43ClN2O9CO[C@@H]1C=CC=C(C)Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)C(C)C)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2 | 25mg | 704981316
Ansamitocin P 3 | Broadpharm | 66584-72-3635.150 | C32H43ClN2O9CO[C@@H]1C=CC=C(C)Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)C(C)C)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2 | 25mg | 704981316
Enzo Life Sciences Cytochalasin B, (5mg), CAS Number: 14930-96-2
Ultra-pure; inhibits actin polymerization. Cytochalasin B is a cell-permeable fungal toxin which binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. It causes the disruption of actin filaments and inhibition of actin polymerization. It also inhibits monosaccharide transport across cell membranes. inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells. Formula: C29H37NO5. MW: 479.6. CAS Number: 14930-96-2. Purity: ≥98% (HPLC, TLC). Appearance: White to off-white solid. Solubility: Soluble in methanol or DMSO (20mg/ml). Long Term Storage: -20°C
Sigma Aldrich Fine Chemicals Biosciences Cholera Toxin B subunit 955MG
Cholera Toxin is a heterohexameric AB5 enterotoxin. Cholera Toxin B subunit is the the B subunit pentamer of cholera toxin produced by Vibrio cholera. It is generally involved in the cell trafficking and signalling machineries.
AdipoGen Latrunculin A,Chemical. CAS: 76343-93-6.
Latrunculin A, AdipoGen Life Sciences. Chemical. CAS: 76343-93-6. Formula: C22H31NO5S. MW: 421.6. Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion. Acts via a different mechanism than cytochalasins. 76343-93-6
Crescent Chemical Co Inc CYTOCHALASIN B
Cytochalasin B From Helminthosporium dematoideum. Reversible inhibitor of cell motion (1). Inhibits phagocytosis (2). Induces polyploidy (3). Induces nuclear extrusion (4, 5). Size - 1MG Storage Conditions - +2 °C TO +8 °C Catalog Number - 18015.
Medchemexpress LLC Mycophenolic acid | 24280-93-1 | 100 MG
Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. It demonstrates antiviral effects against a wide range of RNA viruses, including influenza, dengue virus, Zika virus, rotavirus, CCHFV, and hantavirus. This immunosuppressive agent also exhibits antiangiogenic and antitumor effects.
- Potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor.
- Demonstrates antiviral effects against various RNA viruses.
- Acts as an immunosuppressive agent.
- Exhibits antiangiogenic and antitumor effects.
- Shows preferential antiproliferative activity against endothelial cells and fibroblasts.
- Can down-regulate HDAC2 and MYC, and up-regulate NDRG1.