Non-Mammalian ORFs
Sino Biological SARS-CoV-2 (2019-nCoV) Spike S2 Gene ORF cDNA clone expression plasmid, N-His tag (Codon Optimized)
Full length Clone DNA of SARS-CoV-2 (2019-nCoV) Spike(S2).
ABclonal Technology HCoV-229E Spike S2 Rabbit mAb
S1 region attaches the virion to the cell membrane by interacting with host ANPEP aminopeptidase N initiating the infection Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion S2 region belongs to the class I viral fusion protein Under the current model the protein has at least 3 conformational states pre-fusion native state pre-hairpin intermediate state and post-fusion hairpin state During viral and target cell membrane fusion the coiled coil regions (heptad repeats regions assume a trimer-of-hairpins structure positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes
Sino Biological SARS-CoV-2 (2019-nCoV) Spike S1 ORF mammalian expression plasmid (Codon Optimized)
Full length Clone DNA of SARS-CoV-2 (2019-nCoV) Spike(S1).
Sino Biological SARS-CoV-2 (2019-nCoV) Spike S2 Gene ORF cDNA clone expression plasmid, C-FLAG tag (Codon Optimized)
Full length Clone DNA of SARS-CoV-2 (2019-nCoV) Spike(S2).
Sino Biological Human coronavirus(HCoV-NL63) Spike Gene ORF cDNA clone expression plasmid (Codon Optimized)
Full length Clone DNA of Human coronavirus (HCoV-NL63) Spike.
Cayman Chemical SARSCoVSARSCoV2 SpIke Gly 50uL
An a1-AR antagonist binds to a1-ARs in rat brain membranes (Ki 12.5 nM) inhibits a1-AR agonist-induced contractions in endothelium-denuded isolated rat aortic rings and perfused mesenteric vascular beds (pA2s 8.6 and 11.1 respectively) inhibits cirazoline-induced pressor responses in rats at 0.5 Ug/kg per minute i.v. improves postischemic glutamate uptake and reduces neuronal cell death and mortality in a rat model of global brain ischemia induced by mild hyperthermia at 32 mg/kg increases corneal NGF levels and accelerates corneal wound healing in a rat model of ocular injury
Sino Biological SARS-CoV-2 (2019-nCoV) Spike S2 Gene ORF cDNA clone expression plasmid, C-His tag (Codon Optimized)
Full length Clone DNA of SARS-CoV-2 (2019-nCoV) Spike(S2).
Sino Biological SARS-CoV-2 (2019-nCoV) Spike S1 Gene ORF cDNA clone expression plasmid, C-FLAG tag (Codon Optimized)
Full length Clone DNA of SARS-CoV-2 (2019-nCoV) Spike(S1).
Sino Biological Human Coronavirus spike glycoprotein Gene ORF cDNA clone expression plasmid (Codon Optimized), N-Flag tag
Full length Clone DNA of Human coronavirus (isolate HKU1) Spike glycoprotein.
ABclonal Technology HCoV-229E Spike S1 Rabbit mAb
S1 region attaches the virion to the cell membrane by interacting with host ANPEP aminopeptidase N initiating the infection Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion S2 region belongs to the class I viral fusion protein Under the current model the protein has at least 3 conformational states pre-fusion native state pre-hairpin intermediate state and post-fusion hairpin state During viral and target cell membrane fusion the coiled coil regions (heptad repeats regions assume a trimer-of-hairpins structure positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes
Cayman Chemical SARSCoVSARSCoV2 SpIke Gly 50uL
An a1-AR antagonist binds to a1-ARs in rat brain membranes (Ki 12.5 nM) inhibits a1-AR agonist-induced contractions in endothelium-denuded isolated rat aortic rings and perfused mesenteric vascular beds (pA2s 8.6 and 11.1 respectively) inhibits cirazoline-induced pressor responses in rats at 0.5 Ug/kg per minute i.v. improves postischemic glutamate uptake and reduces neuronal cell death and mortality in a rat model of global brain ischemia induced by mild hyperthermia at 32 mg/kg increases corneal NGF levels and accelerates corneal wound healing in a rat model of ocular injury
Cayman Chemical SARSCoVSARSCoV2 SpIke Gly 50uL
An a1-AR antagonist binds to a1-ARs in rat brain membranes (Ki 12.5 nM) inhibits a1-AR agonist-induced contractions in endothelium-denuded isolated rat aortic rings and perfused mesenteric vascular beds (pA2s 8.6 and 11.1 respectively) inhibits cirazoline-induced pressor responses in rats at 0.5 Ug/kg per minute i.v. improves postischemic glutamate uptake and reduces neuronal cell death and mortality in a rat model of global brain ischemia induced by mild hyperthermia at 32 mg/kg increases corneal NGF levels and accelerates corneal wound healing in a rat model of ocular injury
Sino Biological SARS-CoV-2 (2019-nCoV) Spike RBD Gene ORF cDNA clone expression plasmid, N-His tag (Codon Optimized)
Full length Clone DNA of SARS-CoV-2 (2019-nCoV) Spike(RBD).
Sino Biological SARS-CoV-2 (2019-nCoV) Nucleoprotein Gene ORF cDNA clone expression plasmid, C-His tag (Codon Optimized)
Full length Clone DNA of SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP.
ABclonal Technology HCoV-229E Spike S2 Rabbit mAb
S1 region attaches the virion to the cell membrane by interacting with host ANPEP aminopeptidase N initiating the infection Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion S2 region belongs to the class I viral fusion protein Under the current model the protein has at least 3 conformational states pre-fusion native state pre-hairpin intermediate state and post-fusion hairpin state During viral and target cell membrane fusion the coiled coil regions (heptad repeats regions assume a trimer-of-hairpins structure positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes