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EF1a-H3 3-K27M-Flag/BSD lentiviral vector expressing Flag under EF1a promoter Each vial provides a nominal titer of 2x10E6 transducing units TU Human H3 3 K27M ORF cDNA lentivirus Lentiviral particles packaged with expression vector for K27M mutant of human H3 3 histone A (also known as H3 3 or H3-3A) transcript variant 1 An EF1 promoter drives expression of H3 3 K27M fused to a C-terminal V5 tag and a GFP reporter which is separated from the ORF cDNA by a self-cleaving peptide These lentiviral particles allow for easy transduction and high stable expression of the indicated ORF cDNA in mammalian cells The lentiviral vectors have been optimized to provide high gene expression and reliable genome integration allowing for easy establishment of long-term stable cell lines with consistent read out of fluorescent (GFP RFP) or luminescent (firefly luc) reporters
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
h/m BCL-xL-sh-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m BCL-xL shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse BCL2 like 1 (BCL-xL) The shRNA has been validated to meet or exceed 70% BCL-xL knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A flavonoid with diverse biological activities; inhibits sPLA2 (IC50 = 17.6 µM); decreases protein levels of Akt and induces apoptosis in NCI H460 NSCLC cells at 12.5, 25, and 50 µM; scavenges DPPH radicals and superoxide anions in cell-free assays at 200 UG/ml; reduces TPA-induced EAr edema and carrageenan-induced paw edema in mice at 150 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
The ISRE Luciferase Reporter HEK293 Cell Line (JAK/STAT Signaling Pathway) is a HEK293 cell line designed to monitor the activity of the JAK (Janus kinase)/STAT (Signal Transducer and Activator of Transcription) signaling pathway. These cells expresses a firefly luciferase reporter driven by ISRE (interferon stimulated response element) stably integrated into HEK293 cells.This cell line has been shown to be responsive to stimulation with IFNα (interferon Alpha) and to treatment with the JAK inhibitor Pyridone 6.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More