General Cell Based Assays
Eurofins Discoverx PathHunter eXpress HTR1B U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0697E3CP6M)
The PathHunter HTR1B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of HTR1B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR1B and EA-tagged β-Arrestin-2. Activation of HTR1B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human IL-22 (IL22RA1/IL10RB) Dimerization Cell-Based Assay Kit (HEK 293)
The PathHunter Human IL-22 (IL22RA1/IL10RB) Stable Cell Line Dimerization Assay (HEK 293) measures ligand-induced dimerization of IL22RA/IL10RB1. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
MOLTOX Molecular Toxicology Inc 60-250.5 - NADPH REGENSYS A Plus. 50ml refers to final volume of S9 mix/pkg. Intended for use in EAT testing. Supports 5-30% S9 mix. G-6-P MgCl2-KCL in 0.1M phosphate buffer. pH 7.4. Add to B Plus. Refrigerate.
60-250.5 - NADPH REGENSYS A Plus. 50ml refers to final volume of S9 mix/pkg. Intended for use in EAT testing. Supports 5-30% S9 mix. G-6-P MgCl2-KCL in 0.1M phosphate buffer. pH 7.4. Add to B Plus. Refrigerate.
Eurofins Discoverx PathHunter MRGPRX2 Bioassay Kit, 2-Plate. (93-0309Y2-00143)
The PathHunter MRGPRX2 Bioassay kit provides a robust, highly sensitive, and easy-to-use functional cell based assay to measure drug potency and detect neutralizing antibodies. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility, and faster implementation from characterization to lot release. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress rHTR2C U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0915E3RCP0M)
The PathHunter rHTR2C eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of rHTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rHTR2C and EA-tagged β-Arrestin-2. Activation of rHTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0426
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0426
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0603
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0603
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0462
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0462
Eurofins Discoverx cAMP Hunter™ Human ADORA3 (A3) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human ADORA3 (A3) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADORA3 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human VIPR2 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human VIPR2 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure VIPR2 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GALR1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human GALR1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure GALR1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.