General Cell Based Assays
Eurofins Discoverx cAMP Hunter eXpress DRD2S (Short Isoform) CHO-K1 GPCR Assay, 2pl Kit. (95-0084E2CP2M)
The cAMP Hunter DRD2S eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD2S GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type DRD2S, a naturally Gi/Go coupled GPCR. Upon activation of DRD2S, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences Rap1 Assay Reagent Ral GDS
Product Source expressed in E. coli
Eurofins Discoverx cAMP Hunter eXpress ADRB1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0113E2CP2L)
The cAMP Hunter ADRB1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADRB1, a naturally Gs coupled GPCR. Upon activation of ADRB1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress MC3R U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0984E3CP5M)
The PathHunter MC3R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC3R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC3R and EA-tagged β-Arrestin-2. Activation of MC3R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Human MC5R Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human MC5R Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MC5R (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LGR4 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human LGR4 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure LGR4 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR141 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR141 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR141 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human HRH3 (H3) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human HRH3 (H3) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure HRH3 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human Complement C5a (C5AR1) Gi cAMP Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human Complement C5a (C5AR1) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure C5AR1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress rHTR2C U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0915E3RCP0M)
The PathHunter rHTR2C eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of rHTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rHTR2C and EA-tagged β-Arrestin-2. Activation of rHTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Bioassay Systems EnzyChrom™ Aconitase Assay Kit. For quantitative determination of aconitase enzyme activity and high-throughput screening assays for aconitase modulator.
For quantitative determination of aconitase enzyme activity and high-throughput screening assays for aconitase modulator. Key Features: Fast and sensitive. Linear detection range (20 µL sample): 0.5 to 100 U/L for 20 min reaction. Convenient and high-throughput. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handlingsystems for processing thousands of samples per day. Method: OD565nm. Samples: Biological samples (e.g. cell lysate, tissue homogenate, serum, etc.). Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 0.5 U/L.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-VASP (Ser157) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-VASP (Ser157) Detection Kit, 10,000 Assay Points
Abcam Ethanol Assay Kit
Ethanol Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery U-PLEX Human ICAM-1 ASY
The Meso Scale Discovery U-PLEX Human ICAM-1 Assay Kit is designed to quantitatively measure Intercellular Adhesion Molecule 1 (ICAM-1) in human serum plasma and cell culture supernatants using an electrochemiluminescent detection method This assay kit includes a 96-well plate coated with capture antibody detection antibody conjugated to an electrochemiluminescent label calibrator and buffer for sample dilution The assay has a detection range of 78-50 000 pg/mL and exhibits no cross-reactivity with other adhesion molecules This product can aid in understanding ICAM-1 levels related to inflammatory and immune responses
ABclonal Technology Actin (plant specific) Rabbit pAb
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.