General Cell Based Assays
Eurofins Discoverx PathHunter eXpress MC4R U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0211E3CP0L)
The PathHunter MC4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC4R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC4R and EA-tagged β-Arrestin-2. Activation of MC4R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences Lactate Oxidase from Aeroc
LACTATE Lactate Oxidase from Aeroc
Enzo Life Sciences CHEMILUM DE LYS HDAC/SIRT Chemiluminescent drug discovery kit (1x96wells)
The HDAC/SIRT Chemiluminescent Drug Discovery Kit is a complete assay system designed to measure histone deacetylase and sirtuin activity in cell or nuclear extracts, immunoprecipitates or purified enzymes. The HDAC Chemiluminescent Activity Assay is based on the unique CHEMILUM DE LYS Substrate and Developer combination. The CHEMILUM DE LYS system is a highly sensitive and convenient alternative to radiolabeled, acetylated histones or peptide/HPLC methods for the assay of histone deacetylases. The assay procedure has three steps. First, the CHEMILUM DE LYS Substrate, which comprises an acetylated lysine side chain, is incubated with a sample containing HDAC activity . Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the CHEMILUM DE LYS Developer followed by Enhancer produces light. The reaction is luciferase-free Alternative name: Histone deacetylase fluorescent assay kit. Applications: Chemiluminescence, HTS Activity assay.
Meso Scale Discovery RPLEX HUM Folate R alpha ASY
The Meso Scale Discovery R-Plex Human Folate R-alpha Assay Kit is a multiplex immunoassay for measuring folate receptor alpha in human serum plasma and cell culture supernatant It uses electrochemiluminescent detection for high sensitivity broad dynamic range and precision with low sample use The kit includes a 96-well plate with capture antibody detection antibody read buffer calibrator and controls for quantifying folate receptor alpha a key biomarker in human samples
Cayman Chemical 8pIpRIdIno NAD sodIM sal 700ug
A derivative of NAD+; has been used in the determination of PARP target proteins; a synthetic intermediate in the synthesis of cADPR derivatives
Medchemexpress LLC cGAS Human His-SUM 50ug
Recombinant human cyclic GMP-AMP synthase (cGAS) fragment (G161-F522) expressed in E. coli and supplied lyophilized with N-terminal 6xHis and SUMO tags to aid purification and solubility. Supplied amount for this item is 50 μg; other pack sizes are available. Activity testing is in progress and not guaranteed. Store lyophilized material frozen and aliquot after reconstitution per manufacturer's guidance.
- Recombinant fragment spanning residues G161-F522.
- N-terminal 6xHis and SUMO tags for purification and solubility.
- Expressed in E. coli for bacterial expression.
- Lyophilized formulation with trehalose for improved stability.
- Available in multiple pack sizes, including 50 μg.
- Activity testing in progress; no guaranteed activity.
- Recommend aliquoting and storage at -20°C or -80°C for long-term preservation.
Eurofins Discoverx PathHunter eXpress GPR79 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0408E2ACP1M)
The PathHunter GPR79 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR79 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR79 and EA-tagged β-Arrestin-2. Activation of GPR79 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical LIpIdLaunchLNPMC3 Uptake K 1ea
Cayman’s LipidLaunch™ LNP-MC3 Uptake Kit (Near-Infrared Fluorescence) is intended to serve as a starting point for laboratories to explore the uptake of LNPs in vivo without the need for specialized equipment. Optimal preparation conditions for the encapsulation of nucleic acids with LNPs must be determined by the end user.
Revvity Health Sciences Inc HTRF Human Total Phospholamban Detection Kit, 10,000 Assay Points
HTRF Human Total Phospholamban Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc AlphaScreen cAMP Detection Kit, 10,000 Assay Points
AlphaScreen cAMP Detection Kit, 10,000 Assay Points
Meso Scale Discovery R-PLEX Human cIAP1 ASY
The R-Plex Human CIAP1 Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures the levels of Cellular Inhibitor of Apoptosis Protein 1 (CIAP1) in human serum plasma and cell culture supernatants This assay utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The assay can monitor CIAP1 levels across four orders of magnitude from sub-picogram to nanogram levels per mL This quantitative immunoassay allows the study of CIAP1 levels in biological samples for life science research
Eurofins Discoverx PathHunter eXpress GPR109B CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0791E2CP2L)
The PathHunter GPR109B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. 3-hydroxyoctanoic acid) based activation of GPR109B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR109B and EA-tagged β-Arrestin-2. Activation of GPR109B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR15 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0682E2CP1L)
The PathHunter GPR15 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR15 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR15 and EA-tagged β-Arrestin-2. Activation of GPR15 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR6 U2OS β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0634E3CP1L)
The PathHunter GPR6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR6 and EA-tagged β-Arrestin-2. Activation of GPR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress AGTRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0250E2CP0M)
The PathHunter AGTRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of AGTRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AGTRL1 and EA-tagged β-Arrestin-2. Activation of AGTRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.