General Cell Based Assays
Electron Microscopy Sciences Flim Sleeve 135 mm/36 exp with Frosted Open Flap
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Type: Frosted Open Flap
Eurofins Discoverx PathHunter Flash Detection Kit, 125 (10 plates), 1,000/4,000 dp (96-well/384-well). (93-0247)
The PathHunter Flash Detection Kit is a detection kit intended for use with PathHunter cell lines or with custom cell lines made using ProLabel/PK expression vectors. This kit will provide a brighter signal with shorter kinetics than the PathHunter Detection Kit, at the cost of a shorter half life. It can be substituted in and used with any cell line that specifies use of the PathHunter Detection kit. This kit contains lysis buffer and EFC substrate to allow for detection of EFC levels in the assayed cells. This kit contains all components required to assay 10 plates (96/384-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-93-0247.
Eurofins Discoverx PathHunter eXpress SCTR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0237E2CP0M)
The PathHunter SCTR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SCTR and EA-tagged β-Arrestin-2. Activation of SCTR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cell Biolabs Inc CytoSelect™ 48-Well Cell Contraction Assay Kit (Floating Matrix Model), 48 assays
Several culture models exist to study fibroblasts' ability of to reorganize and contract collagen matrices in vitro. In the floating matrix contraction model, a freshly polymerized collagen matrix containing cells is released from the culture dish and allowed to float in culture medium, and contraction occurs in the absence of external mechanical load and without appearance of stress fibers in the cells. The CytoSelect™ 48-Well Cell Contraction Assay Kit provides a simple system to assess cell contractivity in vitro and screen cell contraction mediators using the floating matrix model. The kit's proprietary Cell Contraction Plate eliminates the matrix releasing step of the conventional contraction assay, providing a faster, higher-throughput method to assess cell contraction. Each kit provides sufficient quantities to perform up to 48 assays in a 48-well plate.
Meso Scale Discovery R-PLEX Human ACE2 ASY
The R-PLEX Human ACE2 Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures human angiotensin-converting enzyme 2 (ACE2) levels in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The assay can help monitor ACE2 levels which may be relevant in COVID-19 infection and research This 10-plex assay includes a total of 10 analytes including human ACE2 and 9 other biomarkers
Revvity Health Sciences Inc HTRF Human & Mouse Total PLC-γ1 Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Total PLC-γ1 Detection Kit, 10,000 Assay Points
Eurofins Discoverx AssayComplete Cell Plating 5 Reagent, 100. (93-0563R5A)
AssayComplete Cell Plating 5 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress EGFR/ErbB2 Dimerization Assay, 2-Plate Kit. (93-1051E3CP14M)
The PathHunter EGFR/ErbB2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. EGF) induced dimerization of EGFR/ErbB2 receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of EGFR/ErbB2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HTR2A U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0401E3CP19L)
The PathHunter HTR2A eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of HTR2A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2A and EA-tagged β-Arrestin-2. Activation of HTR2A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress EphB2 Functional Assay, 2-Plate Kit. (93-0848E3CP16M)
The PathHunter eXpress EphB2 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB2 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB2 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress P2RY6 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0500E2CP19M)
The PathHunter P2RY6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. UTP) based activation of P2RY6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY6 and EA-tagged β-Arrestin-2. Activation of P2RY6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Bioassay Systems EnzyChrom™ Lactose Assay Kit. For quantitative determination of lactose and evaluation of drug effects on lactose metabolism.
For quantitative determination of lactose and evaluation of drug effects on lactose metabolism. Key Features: Sensitive. Use as little as 20 µL samples. Linear detection range in 96-well plate: 17 to 2000 µM lactose for colorimetric assays and 6 to 100 µM for fluorimetric assays. Convenient and high-throughput. Robust and homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: OD570nm, or FL530/585nm. Samples: Biological (milk), food and agriculture etc. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 6 µM.
Echelon Biosciences Research Labs High Throughput Autotaxin Inhibitor Screening Kit
The Autotaxin Inhibitor Screening Kit utilizes purified autotaxin (ATX) and the autotaxin substrate FS-3, which fluoresces upon cleavage. The assay is performed in a 96 well plate and quantifies the autotaxin activity in the presence of the users samples by measuring changes in fluorescence over time.Sample Type: Inhibitors against ATXSample Volume: 10 L/ well of your sample compoundsSample Considerations: Some organic solvents interfere with the assay (see technical data sheet). This item is non returnable
Eurofins Discoverx AssayComplete Cell Plating 24 Reagent, 500. (93-0563R24B)
AssayComplete Cell Plating 24 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Meso Scale Discovery U-PLEX Human A2M ASY
The Meso Scale Discovery U-PLEX Human A2M Assay is a multiplex immunoassay kit for measuring Alpha-2-Macroglobulin (A2M) in human serum plasma and cell culture supernatant This electrochemiluminescent assay uses MSD s SECTOR Imager offering high sensitivity a broad dynamic range and low sample volume The kit includes a 96-well plate with capture antibodies detection antibodies and necessary calibrators and controls It enables rapid reproducible quantification of A2M crucial for regulating protease activity