General Cell Based Assays
Cayman Chemical 8-pCPT NAD sodIum salt 800ug
A derivative of NAD+; has been used in the screening of analog-sensitive PARP1 gatekeeper mutations
Cayman Chemical 8-cPeT NAD sodIum salt 800ug
A derivative of NAD+; has been used in the screening of analog-sensitive PARP1 gatekeeper mutations
Meso Scale Discovery U-PLEX Human Adiponectin ASY
The Meso Scale Discovery U-PLEX Human Adiponectin Assay Kit quantifies adiponectin in human serum plasma and cell culture supernatants using electrochemiluminescent detection It features MSD s SULFO-TAG labels and multi-array plate technology for high sensitivity and minimal interference The kit includes a 96-well plate with capture antibodies detection antibodies with ruthenium labels calibrators and necessary reagents The assay takes about 3 5 hours facilitating adiponectin measurement in studies on obesity diabetes and cardiovascular disease
Meso Scale Discovery U-PLEX Rat Leptin ASY 25 PL
The Meso Scale Discovery U-PLEX Rat Leptin Assay Kit is a multiplex immunoassay that measures leptin levels in rat serum plasma and cell culture supernatants The assay uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with MSD SULFO-TAG calibrators and controls The assay has a lower limit of detection of 1 3 pg/mL and an upper limit of quantification of 10 000 pg/mL for leptin
Revvity Health Sciences Inc LANCE Ultra cAMP Detection Kit, 50,000 Assay Points
LANCE Ultra cAMP Detection Kit, 50,000 Assay Points
Biolegend ELISA MAXTM Deluxe Set Human S
ELISA MAX™ Deluxe Set Human ST2; Reactivity: Human; Apps: ELISA; Size: 5 Plates
FOCUS BIOMOLECULES Biochemical Reagents, LXG6403, Lysyl oxidase inhibitor, CAS 315705-04-5, 98% by TLC/NMR (Conforms)
Biochemical Reagents, LXG6403, Lysyl oxidase inhibitor, CAS 315705-04-5, 98% by TLC/NMR (Conforms), LXG6403 is a potent (IC50 1.3 uM) and selective (3.5x over LOXL2 and no inhibition of LOX1) lysyl oxidase (LOX) inhibitor. Active against LOX in multiple cell lines (IC50 less than5 uM against MDA-MB-231, HCC143, Hs-578-T, and HCC1937). LXG6403 enhanced chemosensitivity of triple negative breast cancer cells to anthracycline, doxorubicin, cisplatin, and paclitaxel. It inhibited collagen crosslinking and deposition, increased doxorubicin penetration in cells and organoids, inhibited FAK signaling, and potentiated ROS/DNA damage axis in combination with cisplatin. LXG6403 was able to overcome doxorubicin resistance in the TM01278 TNBC PDX model.
Eurofins Discoverx PathHunter eXpress KDR Activity Assay, 10-Plate Kit. (93-0903E3CP16L)
The PathHunter KDR Activity eXpress kit provides an easy-to-use cell based assay to study small molecule drug candidates targeting RTKs. This kit assesses RTK activation via detection of resulting KDR phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The cell line overexpresses ProLink-tagged fusion of the KDR kinase domain with transmembrane and extracellular ligand binding domain of EGFR; and also an EA-tagged SH2 domain protein. Upon ligand induced receptor activation, cross-phosphorylation of the receptor leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress KDR Activity Assay, 2-Plate Kit. (93-0903E3CP16M)
The PathHunter KDR Activity eXpress kit provides an easy-to-use cell based assay to study small molecule drug candidates targeting RTKs. This kit assesses RTK activation via detection of resulting KDR phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The cell line overexpresses ProLink-tagged fusion of the KDR kinase domain with transmembrane and extracellular ligand binding domain of EGFR; and also an EA-tagged SH2 domain protein. Upon ligand induced receptor activation, cross-phosphorylation of the receptor leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human IL-36 ASY
The Meso Scale Discovery R-PLEX Human IL-36gamma Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of IL-36gamma in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements This assay kit includes a plate coated with capture antibodies detection antibodies labeled with an ECL compound and calibrator and control solutions for generating standard curves and evaluating run validity It allows sensitive reproducible quantification of IL-36gamma levels from human samples
Eurofins Discoverx AssayComplete Thawing Reagent T6, 100. (92-4106TR)
AssayComplete Thawing Reagent T6 is an optimized thawing reagent for revival and recovery of Eurofins DiscoverX cell lines. This reagent ensures optimal post-thaw viability, recovery and assay performance upon thawing. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended thawing reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
ABclonal Technology Actin (plant specific) Rabbit pAb
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.