General Cell Based Assays
Eurofins Discoverx PathHunter eXpress IL4R/IL13RA1 Dimerization Assay, HEK293, 2pl Kit. (93-1001E1CP0M)
The PathHunter IL4R/IL13RA1 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-13) induced dimerization of IL4R/IL13RA1 receptors. This product uses EFC technology. The cell line included overexpresses IL4R target protein fused to PK alongside IL13RA1 target protein fused to EA. Upon ligand-induced dimerization of IL4R/IL13RA1, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
American Research Products Inc DLX3 Transcription Factor Activity Assay
DLX3 Transcription Factor Activity Assay
Eurofins Discoverx PathHunter Human GPR18 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR18 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR18 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter eXpress CRHR1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0047E2CP2L)
The cAMP Hunter CRHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CRH, sauvagine) based activation of CRHR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CRHR1, a naturally Gs coupled GPCR. Upon activation of CRHR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Molecular Devices Membrane Potential Assay Kit, Explorer, Blue Dye, 96/384-Well
The FLIPR Membrane Potential Assay Kit (Explorer format, Blue) is a homogeneous fluorescence reagent kit for detecting changes in cellular membrane potential in high-throughput screening. The kit simplifies assay setup with prealiquoted dye vials and assay buffer, and is compatible with common plate readers and FLIPR systems.
- Homogeneous, no-wash fluorescence assay for membrane potential detection.
- Includes 10 reagent vials and 1 bottle of assay buffer.
- Blue membrane potential dye formulated for sensitive detection.
- Suitable for 96-well and 384-well plate formats.
- Each vial supplies reagent for one plate to simplify assay setup.
- Intended for research use only; not for diagnostic procedures.
Eurofins Discoverx PathHunter eXpress GPR182 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0754E2CP1M)
The PathHunter GPR182 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR182 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR182 and EA-tagged β-Arrestin-2. Activation of GPR182 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Human mGlu2 (GRM2) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human mGlu2 (GRM2) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GRM2 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human PTHR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human PTHR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PTHR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0481
PhosphoSens-Kinetic Phosphatase Activity Kit 1000 assays - AQT0481
Eurofins Discoverx PathHunter eXpress mAGTRL1 CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0565E2MCP0L)
The PathHunter mAGTRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of mAGTRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mAGTRL1 and EA-tagged β-Arrestin-2. Activation of mAGTRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc Tag-lite SNAP/CLIP Labeling Medium (5X), 100 mL
Tag-lite SNAP/CLIP Labeling Medium (5X), 100 mL
Cayman Chemical NAD free acId 5g
A signaling molecule as well as a cofactor or substrate for many enzymes
Eurofins Discoverx PathHunter eXpress CXCR5 (BLR1) CHO-K1 β-Arrestin GPCR Assay, 2pl Kit. (93-0514E2CP2M)
The PathHunter CXCR5 (BLR1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL13/BCA-1/BLC) based activation of CXCR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR5 and EA-tagged β-Arrestin-2. Activation of CXCR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GHSR1b CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0354E2ACP1M)
The PathHunter GHSR1b eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. ghrelin) based activation of GHSR1b GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1b and EA-tagged β-Arrestin-2. Activation of GHSR1b stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx InCELL Hunter eXpress CLK2 Kinase Binding Assay, 10pl Kit. (96-0057E15CP0L)
The InCELL Hunter eXpress CLK2 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of CLK2 via detection of CLK2 levels. This product uses EFC technology. The cell line included overexpresses CLK2 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.