General Cell Based Assays
Meso Scale Discovery U-PLEX Mouse Leptin ASY
The Meso Scale Discovery U-PLEX Mouse Leptin Assay Kit is a multiplex immunoassay that measures mouse leptin in serum plasma and cell culture supernatants It uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision The assay requires 50 L or less sample volume and takes 3 5 hours to complete It includes a 96-well plate coated with capture antibodies detection antibodies labeled with MSD SULFO-TAG calibrators and controls The kit has a sensitivity of 0 3 pg/mL and an upper limit of quantitation of 10 000 pg/mL for leptin
Meso Scale Discovery RPLEX HUM Cytokeratin19 ASY
The R-PLEX Human Cytokeratin 19 Assay Kit from Meso Scale Diagnostics is a multiplex immunoassay that quantitatively measures cytokeratin 19 levels in human serum plasma and cell culture supernatant samples The assay utilizes electrochemiluminescent detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies calibrators and reagents required for the assay It can be used for cancer biomarker research and measuring treatment response The assay has a lower limit of detection of 0 016 ng/mL and an upper limit of quantification of 400 ng/mL for cytokeratin 19
Eurofins Discoverx cAMP Hunter eXpress GRM6 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0105E2CP24M)
The cAMP Hunter GRM6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. L-glutamate) based activation of GRM6 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GRM6, a naturally Gi/Go coupled GPCR. Upon activation of GRM6, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress rDRD2L (Long Isoform) CHO-K1 GPCR Assay, 2pl Kit. (95-0130E2CP2M)
The cAMP Hunter rDRD2L eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine, pergolide) based activation of rDRD2L GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type rDRD2L, a naturally Gi/Go coupled GPCR. Upon activation of rDRD2L, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Bioassay Kit ED Detection Kit, 10 (200 dp, 96-well). (93-1043E)
The PathHunter Bioassay ED Detection Kit is a detection kit intended for use with Eurofins DiscoverX's PathHunter Bioassay cells overexpressing ED (ProLabel/PK) but not containing any EA. This kit contains lysis buffer, exogenous EA, and EFC substrate to allow for detection of levels of ED in the assayed cells. This kit contains all components required to assay 2 plates (96-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-93-1043e.
Eurofins Discoverx PathHunter eXpress GPR39 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0338E2CP1M)
The PathHunter GPR39 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR39 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR39 and EA-tagged β-Arrestin-2. Activation of GPR39 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR92 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0372E2CP6L)
The PathHunter GPR92 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. LPA) based activation of GPR92 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR92 and EA-tagged β-Arrestin-2. Activation of GPR92 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress PTGER3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0640E2CP0L)
The PathHunter PTGER3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin E2) based activation of PTGER3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTGER3 and EA-tagged β-Arrestin-2. Activation of PTGER3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human Renin ASY
The R-PLEX Human Renin Assay from Meso Scale Discovery is a multiplex immunoassay that measures active renin in human serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity a broad dynamic range and requires a low sample volume The assay can be fully automated and has a rapid 2 5 hour turnaround time The R-PLEX assay quantitatively measures renin levels and is designed for use in biomarker research drug discovery and development This product requires the MSD QuickPlex SQ120 instrument and provides components for 96 tests in the kit
Eurofins Discoverx cAMP Hunter eXpress GRM6 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0105E2CP24L)
The cAMP Hunter GRM6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. L-glutamate) based activation of GRM6 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GRM6, a naturally Gi/Go coupled GPCR. Upon activation of GRM6, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress NPFFR1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0097E2CP2M)
The cAMP Hunter NPFFR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuropeptide FF, RFRP-3) based activation of NPFFR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type NPFFR1, a naturally Gi/Go coupled GPCR. Upon activation of NPFFR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress LHCGR CHO-K1 GPCR Assay, 10-Plate Kit. (95-0106E2CP2L)
The cAMP Hunter LHCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. luteinizing hormone) based activation of LHCGR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type LHCGR, a naturally Gs coupled GPCR. Upon activation of LHCGR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mADORA2B CHO-K1 β-Arrestin GPCR Assay, 2pl Kit. (93-0469E2MCP0M)
The PathHunter mADORA2B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. NECA) based activation of mADORA2B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mADORA2B and EA-tagged β-Arrestin-2. Activation of mADORA2B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.