General Cell Based Assays
Eurofins Discoverx PathHunter eXpress PROKR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0303E2CP0L)
The PathHunter PROKR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokinectin, EG-VEGF) based activation of PROKR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PROKR1 and EA-tagged β-Arrestin-2. Activation of PROKR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
