General Cell Based Assays
Apexbio Technology LLC DiscoveryProbe™ PI3K/Akt/mTOR Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
The DiscoveryProbe PI3K/Akt/mTOR Compound Library comprises 178 small molecule inhibitors targeting PI3K/Akt/mTOR-related signaling pathways This pathway regulates processes such as cell growth proliferation survival apoptosis and metabolism in various cell types making it a frequent focus for oncology and disease mechanism research The collection encompasses compounds approved by regulatory agencies including FDA and EMA and agents studied extensively in academic and pharmaceutical research settings Representative inhibitors within this library include PI3K-selective inhibitors ATM/ATR inhibitors (DNA damage response regulators) and DNA-PK and GSK-3 targeting compounds providing comprehensive coverage for biological pathway elucidation drug discovery screening and pharmacological mechanism-of-action studies
Echelon Biosciences Research Labs PI(4,5)P2 DiC4 500 ug
Phosphatidylinositol 4,5-bisphosphate diC4 (PI(4,5)P2 diC4) is a synthetic, purified dibutanoyl PI(4,5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K). This item is non returnable
Meso Scale Discovery R-PLEX Human IL-19 ASY
The R-PLEX Human IL-19 Assay Kit from Meso Scale Discovery is a multiplex immunoassay for measuring IL-19 in human serum plasma and cell culture supernatants It uses MSD s electrochemiluminescent detection technology offering high sensitivity a 5-log dynamic range and low sample volume needs The kit includes a 96-well plate with capture antibodies for IL-19 detection antibodies calibrators and diluents The assay takes about 3 5 hours and detects IL-19 as low as 17 pg/mL making it a sensitive and efficient tool for quantifying IL-19 in biological samples
Meso Scale Discovery U-PLEX Human Adiponectin ASY
The Meso Scale Discovery U-PLEX Human Adiponectin Assay Kit quantifies adiponectin in human serum plasma and cell culture supernatants using electrochemiluminescent detection It features MSD s SULFO-TAG labels and multi-array plate technology for high sensitivity and minimal interference The kit includes a 96-well plate with capture antibodies detection antibodies with ruthenium labels calibrators and necessary reagents The assay takes about 3 5 hours facilitating adiponectin measurement in studies on obesity diabetes and cardiovascular disease
Meso Scale Discovery R-PLEX Rat IL-1 ASY
The R-PLEX Rat IL-1alpha Assay from Meso Scale Discovery is a multiplex immunoassay that measures rat interleukin 1 alpha (IL-1alpha) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra-/inter-assay precision The assay requires 50 L or less sample volume and can be run on Meso Scale Discovery s QuickPlex SQ 120 QuickPlex SQ 120 Pro or QuickPlex SQ 240 instruments The assay has a lower limit of detection of 0 04 pg/mL and an upper limit of quantification of 2500 pg/mL for rat IL-1alpha
Eurofins Discoverx cAMP Hunter Follitropin Alfa Bioassay Kit, 2pl. (95-0119Y2-00103)
The cAMP Hunter Follitropin Alfa Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses Follitropin Alfa based activation of FSHR GPCR activity via detection of levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type FSHR, a naturally Gs coupled GPCR. Upon activation of FSHR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Abcam Paraoxonase 1 Activity Assay Kit
Paraoxonase 1 Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam GFP QUANTIFICATION KIT, 100 tests
GFP QUANTIFICATION KIT, 100 tests
The product is subject to the following: Abcam Restricted Use Statement
Abcam Hemoglobin Assay Kit (Colorimetric)
Hemoglobin Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx cAMP Hunter eXpress LHCGR CHO-K1 GPCR Assay, 10-Plate Kit. (95-0106E2CP2L)
The cAMP Hunter LHCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. luteinizing hormone) based activation of LHCGR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type LHCGR, a naturally Gs coupled GPCR. Upon activation of LHCGR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress OPRD1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0108E2CP2M)
The cAMP Hunter OPRD1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. DADLE, DPDPE) based activation of OPRD1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type OPRD1, a naturally Gi/Go coupled GPCR. Upon activation of OPRD1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.