General Cell Based Assays
Eurofins Discoverx PathHunter Human OPRL1 (Opioid) Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human OPRL1 (Opioid) Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure OPRL1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse MIP-1 alpha (CCR1) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Mouse MIP-1 alpha (CCR1) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure mCCR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ABclonal Technology Phospho-Lamin A/C-S22 Rabbit pAb
The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Cayman Chemical THUNDRPhosphop38a MAPK 9600Wel
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-p38αβγ MAPK14/11/12 (T180/Y182) in cell lysates
Eurofins Discoverx PathHunter eXpress GPR88 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0357E2ACP1M)
The PathHunter GPR88 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR88 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR88 and EA-tagged β-Arrestin-2. Activation of GPR88 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
TOPOGEN INC DNA Gyrase/Relaxed DNA Assay Kit
The E. coli DNA Gyrase and Relaxed DNA Assay Kit is designed to provide the investigator quick and specific assays for DNA gyrase. These kits facilitate the purification and characterization of gyrase by providing controlled reagents that we certify to work. These kits are also appropriate for the researcher who is interested in large scale screening for novel anti-gyrase active agents. We matched the amount of DNA gyrase enzyme with the amount of relaxed pHOT-1 DNA to get you going and keep you going on the hunt for new actives.
Abcam Alpha Ketoglutarate (alpha KG) Assay Kit
Alpha Ketoglutarate (alpha KG) Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Bioss Actin Fruit Fly Loading Cont
Actin (Fruit Fly Loading Control) Primary Antibody Unconjugated Host Species Rabbit Target Species Clonality Monoclonal Applications WB Concentration 1mg/ml Size 100 ul Storage Buffer 0 01M TBS(pH7 4) with 1% BSA 0 02% Proclin300 and 50% Glycerol
Eurofins Discoverx PathHunter eXpress EDG7 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0636E2CP13M)
The PathHunter EDG7 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. LPA) based activation of EDG7 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDG7 and EA-tagged β-Arrestin-2. Activation of EDG7 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Cell Plating 32 Reagent, 500. (93-0563R32B)
AssayComplete Cell Plating 32 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Cayman Chemical AMPMaxSpec KIt 15test
Cayman’s AMP+ MaxSpec Kit contains a positively charged reagent (AMP+) that can be coupled quantitatively to free carboxylic acids through an amide bond linkage. The resulting derivatized product thus contains a positively charged group that shows improved electrospray ionization and consequently improved MS sensitivity. The derivatization reagent is stable to MS/MS fragmentation and thus isobaric derivatives undergo compound-specific fragmentation to give unique fragment ions.
Eurofins Discoverx cAMP Hunter eXpress GRM6 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0105E2CP24M)
The cAMP Hunter GRM6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. L-glutamate) based activation of GRM6 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GRM6, a naturally Gi/Go coupled GPCR. Upon activation of GRM6, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress BLK Activity Assay, 10-Plate Kit. (93-0882E3CP16L)
The PathHunter eXpress BLK Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the BLK kinase domain. The cell line is engineered to express the catalytic domain from BLK fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the BLK catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Cellular Superoxide Detection Assay Kit.
Cellular Superoxide Detection Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Lipid Staining Kit
Lipid Staining Kit
The product is subject to the following: Abcam Restricted Use Statement